Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3136

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,500,801	-				-4.1
3,500,853	+				-0.2
3,500,909	+				-0.6
3,500,981	-				-0.2
3,501,196	-				+1.4
3,501,375	+		Rv3135	0.10	+0.6
3,501,380	-		Rv3135	0.12	-0.0
3,501,380	-		Rv3135	0.12	+1.4
3,501,380	-		Rv3135	0.12	+1.3
3,501,547	+		Rv3135	0.53	+0.2
3,501,547	+		Rv3135	0.53	-0.0
3,501,548	-		Rv3135	0.54	+0.3
3,501,927	-		Rv3136	0.12	+2.3
3,501,927	-		Rv3136	0.12	+0.5
3,502,008	-		Rv3136	0.19	+2.6
3,502,010	-		Rv3136	0.19	+1.5
3,502,022	+		Rv3136	0.20	+0.9
3,502,094	+		Rv3136	0.26	-0.8
3,502,095	-		Rv3136	0.26	+2.1
3,502,212	-		Rv3136	0.37	+2.3
3,502,247	+		Rv3136	0.40	+2.3
3,502,247	+		Rv3136	0.40	+1.6
3,502,248	-		Rv3136	0.40	+1.3
3,502,254	-		Rv3136	0.40	+2.1
3,502,542	+		Rv3136	0.65	-0.1
3,502,542	+		Rv3136	0.65	+1.7
3,502,946	+				-1.2
3,502,971	+				+2.3
3,502,971	+				-2.0
3,502,972	-				-1.1
3,503,004	-		Rv3136A	0.18	+0.8
3,503,017	+		Rv3136A	0.22	-0.9
3,503,066	+		Rv3136A	0.36	-0.4
3,503,066	+		Rv3136A	0.36	-0.2
3,503,120	+		Rv3136A	0.53	-0.4
3,503,120	+		Rv3136A	0.53	+0.6
3,503,120	+		Rv3136A	0.53	-1.4
3,503,121	-		Rv3136A	0.53	-1.5
3,503,121	-		Rv3136A	0.53	+0.9
3,503,121	-		Rv3136A	0.53	-0.2
3,503,209	-		Rv3136A	0.79	-1.1
3,503,249	-				-0.5
3,503,288	+				-0.4
3,503,365	-				-1.1