Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3110

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,477,781	-		Rv3109	0.12	+0.2
3,478,249	-		Rv3109	0.56	-0.4
3,478,274	-		Rv3109	0.58	+0.7
3,478,357	+		Rv3109	0.66	-0.6
3,478,505	+		Rv3109	0.79	-0.9
3,478,523	-		Rv3109	0.81	-0.4
3,478,544	+		Rv3109	0.83	+2.3
3,478,545	-		Rv3109	0.83	-0.8
3,478,677	-				-0.5
3,478,677	-				-0.1
3,478,685	+				+2.3
3,478,685	+				+1.3
3,478,686	-				-0.3
3,478,849	+		Rv3110	0.18	-1.7
3,478,849	+		Rv3110	0.18	+1.1
3,478,849	+		Rv3110	0.18	-0.0
3,478,849	+		Rv3110	0.18	-0.3
3,478,850	-		Rv3110	0.18	+0.3
3,478,850	-		Rv3110	0.18	-2.0
3,478,850	-		Rv3110	0.18	-0.3
3,478,850	-		Rv3110	0.18	-0.5
3,478,850	-		Rv3110	0.18	+0.3
3,478,850	-		Rv3110	0.18	+0.1
3,478,910	-		Rv3110	0.33	+0.2
3,479,139	+				-0.2
3,479,386	+		Rv3111	0.42	-1.3
3,479,406	+		Rv3111	0.46	-0.5
3,479,504	-		Rv3111	0.65	+1.3
3,479,554	+		Rv3111	0.75	-1.7
3,479,555	-		Rv3111	0.75	+0.3