Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2715

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,027,101	+				+0.8
3,027,125	+				+0.2
3,027,125	+				-0.3
3,027,126	-				-0.7
3,027,126	-				-0.6
3,027,126	-				-0.4
3,027,297	+		Rv2714	0.24	-1.2
3,027,297	+		Rv2714	0.24	-0.8
3,027,324	+		Rv2714	0.27	+0.4
3,027,381	-		Rv2714	0.32	+0.0
3,027,495	+		Rv2714	0.44	-1.6
3,027,710	+		Rv2714	0.66	+0.3
3,027,729	-		Rv2714	0.68	+0.9
3,028,037	+				-0.8
3,028,148	+				+0.1
3,028,224	-		Rv2715	0.12	-0.5
3,028,235	-		Rv2715	0.13	+0.2
3,028,310	-		Rv2715	0.21	+0.2
3,028,348	-		Rv2715	0.24	-0.8
3,028,445	-		Rv2715	0.34	-1.5
3,028,572	-		Rv2715	0.46	-0.2
3,029,117	+				+0.2
3,029,118	-				-0.7
3,029,160	+				+0.3
3,029,160	+				+0.5
3,029,161	-				-1.4
3,029,315	-		Rv2716	0.21	-1.1
3,029,315	-		Rv2716	0.21	-0.1
3,029,367	-		Rv2716	0.28	-0.9
3,029,367	-		Rv2716	0.28	-0.4
3,029,448	-		Rv2716	0.40	-0.3
3,029,448	-		Rv2716	0.40	+1.5
3,029,487	+		Rv2716	0.46	+0.7
3,029,487	+		Rv2716	0.46	+1.3
3,029,616	+		Rv2716	0.65	+0.7
3,029,617	-		Rv2716	0.65	-0.5