Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2706c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,019,446	+				+0.4
3,019,446	+				+0.1
3,019,446	+				-0.5
3,019,674	+		Rv2704	0.50	-1.0
3,019,674	+		Rv2704	0.50	-0.1
3,019,674	+		Rv2704	0.50	-1.2
3,019,675	-		Rv2704	0.51	+0.7
3,019,675	-		Rv2704	0.51	-0.5
3,019,675	-		Rv2704	0.51	-0.4
3,019,675	-		Rv2704	0.51	-0.7
3,019,675	-		Rv2704	0.51	+1.2
3,019,685	+		Rv2704	0.53	-0.9
3,019,796	-		Rv2704	0.79	-0.4
3,019,816	-				-1.8
3,019,819	+				-1.7
3,019,819	+				-0.1
3,019,819	+				+0.1
3,019,820	-				+2.2
3,019,820	-				-0.8
3,019,820	-				-0.8
3,019,926	+		Rv2705c	0.29	-0.6
3,019,960	+		Rv2705c	0.37	+1.6
3,019,961	-		Rv2705c	0.38	-1.2
3,020,092	+		Rv2705c	0.71	+1.0
3,020,092	+		Rv2705c	0.71	+0.1
3,020,093	-		Rv2705c	0.72	+0.1
3,020,093	-		Rv2705c	0.72	-0.2
3,020,095	-		Rv2705c	0.72	-1.0
3,020,095	-		Rv2705c	0.72	+1.5
3,020,165	+				+0.6
3,020,165	+				-0.5
3,020,165	+				-0.3
3,020,166	-				-0.1
3,020,166	-				+0.6
3,020,166	-				+0.2
3,020,356	-		Rv2706c	0.60	-0.9
3,020,572	+				+1.3
3,020,572	+				+1.0
3,020,573	-				+0.7
3,020,626	+				-1.6
3,020,741	+		Rv2707	0.17	-1.9
3,020,741	+		Rv2707	0.17	+0.1
3,020,742	-		Rv2707	0.17	-3.1
3,021,026	+		Rv2707	0.46	+0.4
3,021,026	+		Rv2707	0.46	-1.8
3,021,026	+		Rv2707	0.46	-2.5
3,021,026	+		Rv2707	0.46	-1.6
3,021,027	-		Rv2707	0.47	-1.7
3,021,048	+		Rv2707	0.49	-1.9
3,021,048	+		Rv2707	0.49	-1.8
3,021,048	+		Rv2707	0.49	-1.0
3,021,091	-		Rv2707	0.53	-3.3
3,021,091	-		Rv2707	0.53	+0.4
3,021,140	+		Rv2707	0.58	-1.3
3,021,141	-		Rv2707	0.58	+0.3
3,021,163	-		Rv2707	0.61	-1.6
3,021,183	+		Rv2707	0.63	-1.7
3,021,183	+		Rv2707	0.63	-3.7
3,021,186	-		Rv2707	0.63	-2.3
3,021,199	-		Rv2707	0.64	-1.8
3,021,199	-		Rv2707	0.64	-1.8
3,021,199	-		Rv2707	0.64	-0.3
3,021,231	+		Rv2707	0.67	-1.9
3,021,249	+		Rv2707	0.69	-1.8
3,021,288	-		Rv2707	0.73	-1.9
3,021,314	+		Rv2707	0.76	-3.5
3,021,314	+		Rv2707	0.76	-2.0
3,021,315	-		Rv2707	0.76	+0.7
3,021,320	+		Rv2707	0.77	-1.7
3,021,320	+		Rv2707	0.77	-2.4
3,021,320	+		Rv2707	0.77	-0.1
3,021,321	-		Rv2707	0.77	-1.7
3,021,321	-		Rv2707	0.77	-0.9
3,021,321	-		Rv2707	0.77	-2.2
3,021,321	-		Rv2707	0.77	-1.9
3,021,354	+		Rv2707	0.80	-1.6
3,021,355	-		Rv2707	0.80	-2.1