Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2699c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2697c and Rv2698 are separated by 25 nucleotidesRv2698 and Rv2699c are separated by 4 nucleotidesRv2699c and Rv2700 are separated by 237 nucleotidesRv2700 and Rv2701c are separated by 9 nucleotides Rv2697c: Rv2697c - Probable deoxyuridine 5'-triphosphate nucleotidohydrolase Dut (dUTPase) (dUTP pyrophosphatase) (deoxyuridine 5'-triphosphatase) (dUTP diphosphatase) (deoxyuridine-triphosphatase), at 3,013,683 to 3,014,147 Rv2697c Rv2698: Rv2698 - Probable conserved alanine rich transmembrane protein, at 3,014,173 to 3,014,658 Rv2698 Rv2699c: Rv2699c - Conserved hypothetical protein, at 3,014,663 to 3,014,965 Rv2699c Rv2700: Rv2700 - Possible conserved secreted alanine rich protein, at 3,015,203 to 3,015,853 Rv2700 Rv2701c: Rv2701c - Inositol-1-monophosphatase SuhB, at 3,015,863 to 3,016,735 Rv2701c Position (kb) 3014 3015Strain fitness (log2 ratio) -2 -1 0 1at 3014.661 kb on + strandat 3014.661 kb on + strandat 3014.662 kb on - strandat 3015.073 kb on - strandat 3015.100 kb on - strandat 3015.100 kb on - strandat 3015.100 kb on - strandat 3015.135 kb on + strandat 3015.136 kb on - strandat 3015.136 kb on - strandat 3015.192 kb on - strandat 3015.899 kb on + strandat 3015.899 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL
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3,014,661 + -0.7
3,014,661 + -0.5
3,014,662 - -0.5
3,015,073 - -1.3
3,015,100 - -1.1
3,015,100 - +0.4
3,015,100 - -0.5
3,015,135 + -2.2
3,015,136 - -0.1
3,015,136 - -0.8
3,015,192 - -0.9
3,015,899 + -0.9
3,015,899 + -0.6

Or see this region's nucleotide sequence