Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2674

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,990,639	+				-0.2
2,990,640	-				-0.9
2,990,694	+				-0.3
2,990,694	+				+1.9
2,990,694	+				+0.4
2,990,723	-				-0.0
2,990,817	+		Rv2674	0.27	-1.5
2,990,844	+		Rv2674	0.34	+0.2
2,990,845	-		Rv2674	0.34	+2.2
2,990,845	-		Rv2674	0.34	-0.6
2,991,045	+		Rv2674	0.82	-0.6
2,991,069	+		Rv2674	0.88	+1.2
2,991,069	+		Rv2674	0.88	-0.4
2,991,070	-		Rv2674	0.89	-0.2
2,991,227	-				+2.2
2,991,227	-				+1.1
2,991,227	-				-0.1
2,991,252	+				+0.0
2,991,253	-				-0.0
2,991,298	-		Rv2675c	0.15	+0.5
2,991,326	-		Rv2675c	0.19	-1.1
2,991,353	+		Rv2675c	0.22	-1.0
2,991,371	+		Rv2675c	0.25	+0.5
2,991,372	-		Rv2675c	0.25	+0.4
2,991,479	+		Rv2675c	0.39	-2.3
2,991,479	+		Rv2675c	0.39	-0.9
2,991,525	-		Rv2675c	0.45	-2.5
2,991,563	+		Rv2675c	0.50	-0.9
2,991,563	+		Rv2675c	0.50	+0.4
2,991,564	-		Rv2675c	0.50	+0.4
2,991,564	-		Rv2675c	0.50	-0.6
2,991,719	+		Rv2675c	0.71	-0.1
2,991,720	-		Rv2675c	0.71	-0.5
2,991,735	-		Rv2675c	0.73	-0.3
2,991,737	+		Rv2675c	0.73	+0.8
2,991,738	-		Rv2675c	0.74	-0.3
2,991,887	+				-0.5
2,991,887	+				+0.0
2,991,888	-				-0.5
2,991,888	-				+4.6
2,991,888	-				-0.7
2,991,888	-				+0.1
2,991,888	-				-0.7