Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2626c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2625c and Rv2626c are separated by 58 nucleotidesRv2626c and Rv2627c are separated by 513 nucleotides Rv2625c: Rv2625c - Probable conserved transmembrane alanine and leucine rich protein, at 2,951,322 to 2,952,503 Rv2625c Rv2626c: Rv2626c - Hypoxic response protein 1 Hrp1, at 2,952,562 to 2,952,993 Rv2626c Rv2627c: Rv2627c - Conserved protein, at 2,953,507 to 2,954,748 Rv2627c Position (kb) 2952 2953Strain fitness (log2 ratio) -3 -2 -1 0 1at 2951.579 kb on + strand, within Rv2625cat 2951.693 kb on - strand, within Rv2625cat 2951.963 kb on + strand, within Rv2625cat 2951.986 kb on + strand, within Rv2625cat 2952.759 kb on - strand, within Rv2626cat 2952.914 kb on + strand, within Rv2626cat 2952.914 kb on + strand, within Rv2626cat 2953.020 kb on - strandat 2953.066 kb on - strandat 2953.106 kb on - strandat 2953.201 kb on + strandat 2953.201 kb on + strandat 2953.373 kb on + strandat 2953.746 kb on + strand, within Rv2627cat 2953.925 kb on + strand, within Rv2627cat 2953.926 kb on - strand, within Rv2627c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL
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2,951,579 + Rv2625c 0.22 -1.5
2,951,693 - Rv2625c 0.31 -0.6
2,951,963 + Rv2625c 0.54 +0.0
2,951,986 + Rv2625c 0.56 -0.6
2,952,759 - Rv2626c 0.46 -0.5
2,952,914 + Rv2626c 0.81 -3.1
2,952,914 + Rv2626c 0.81 -1.0
2,953,020 - +0.2
2,953,066 - +1.2
2,953,106 - -0.3
2,953,201 + -0.5
2,953,201 + -0.0
2,953,373 + +0.5
2,953,746 + Rv2627c 0.19 -0.4
2,953,925 + Rv2627c 0.34 +1.2
2,953,926 - Rv2627c 0.34 +0.9

Or see this region's nucleotide sequence