Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2601

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,927,424	+		Rv2598	0.88	-2.6
2,927,579	+		Rv2599	0.24	-0.2
2,927,579	+		Rv2599	0.24	-0.8
2,927,580	-		Rv2599	0.24	+0.0
2,927,678	+		Rv2599	0.47	+0.2
2,927,679	-		Rv2599	0.47	-0.1
2,927,768	+		Rv2599	0.67	-0.1
2,927,768	+		Rv2599	0.67	-0.4
2,927,769	-		Rv2599	0.68	-0.5
2,927,769	-		Rv2599	0.68	-1.1
2,927,807	+		Rv2599	0.76	+4.2
2,927,809	+		Rv2599	0.77	-1.5
2,927,822	+		Rv2599	0.80	-0.1
2,927,822	+		Rv2599	0.80	+0.6
2,927,823	-		Rv2599	0.80	-1.0
2,927,823	-		Rv2599	0.80	+1.7
2,927,906	+				-0.4
2,927,907	-				+0.4
2,927,907	-				-0.3
2,927,907	-				-0.4
2,927,937	-				-1.2
2,927,937	-				-1.2
2,927,937	-				-0.7
2,927,940	-				+1.2
2,927,940	-				+0.2
2,928,009	-				+0.4
2,928,016	-				+1.6
2,928,087	+		Rv2600	0.24	-1.0
2,928,137	+		Rv2600	0.37	-0.4
2,928,137	+		Rv2600	0.37	-2.0
2,928,137	+		Rv2600	0.37	-0.5
2,928,137	+		Rv2600	0.37	+1.0
2,928,137	+		Rv2600	0.37	-0.4
2,928,138	-		Rv2600	0.37	-0.1
2,928,173	+		Rv2600	0.46	+1.9
2,928,173	+		Rv2600	0.46	-1.9
2,928,361	-				-0.2
2,928,568	+		Rv2601	0.11	-1.0
2,928,569	-		Rv2601	0.12	+2.2
2,928,569	-		Rv2601	0.12	+1.2
2,928,569	-		Rv2601	0.12	+3.2
2,928,569	-		Rv2601	0.12	-0.1
2,928,692	-		Rv2601	0.19	+0.8
2,928,929	+		Rv2601	0.34	-0.7
2,928,930	-		Rv2601	0.34	-0.2
2,928,930	-		Rv2601	0.34	+0.4
2,929,043	+		Rv2601	0.42	+0.6
2,929,256	-		Rv2601	0.55	+1.2
2,929,463	+		Rv2601	0.68	-0.1
2,929,464	-		Rv2601	0.68	-1.0
2,929,464	-		Rv2601	0.68	-1.1
2,929,464	-		Rv2601	0.68	+2.9
2,929,464	-		Rv2601	0.68	-0.9
2,929,583	-		Rv2601	0.76	+1.1
2,929,597	+		Rv2601	0.77	-0.7
2,929,597	+		Rv2601	0.77	-1.6
2,929,597	+		Rv2601	0.77	+2.0
2,929,598	-		Rv2601	0.77	-0.1
2,929,598	-		Rv2601	0.77	-2.4
2,929,598	-		Rv2601	0.77	+1.5
2,929,661	-		Rv2601	0.81	+1.6
2,929,730	-		Rv2601	0.85	-0.6
2,929,730	-		Rv2601	0.85	-0.4
2,929,782	+		Rv2601	0.89	-1.2
2,929,782	+		Rv2601	0.89	+0.2
2,929,957	+				+1.6
2,929,970	+				+0.8
2,929,970	+				+0.4
2,930,049	+				+0.2
2,930,423	+		Rv2602	0.18	-0.3
2,930,519	-		Rv2602	0.40	-0.3
2,930,683	+		Rv2602	0.77	+0.2
2,930,684	-		Rv2602	0.77	-1.0
2,930,684	-		Rv2602	0.77	+0.1
2,930,684	-		Rv2602	0.77	-0.6
2,930,684	-		Rv2602	0.77	-1.0
2,930,687	+		Rv2602	0.78	+0.4
2,930,687	+		Rv2602	0.78	+2.2
2,930,703	+		Rv2602	0.81	-0.3
2,930,704	-		Rv2602	0.82	+1.6
2,930,749	+				+0.7
2,930,750	-				+1.2