Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2404c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,700,455	+				-0.2
2,700,455	+				+0.4
2,700,709	+		Rv2403c	0.23	+0.1
2,701,439	-				+2.2
2,701,585	+		Rv2404c	0.15	+3.8
2,701,585	+		Rv2404c	0.15	+2.4
2,701,586	-		Rv2404c	0.15	+3.2
2,701,706	-		Rv2404c	0.21	+3.0
2,701,771	+		Rv2404c	0.25	+2.1
2,701,801	+		Rv2404c	0.26	-0.6
2,701,801	+		Rv2404c	0.26	+2.8
2,701,802	-		Rv2404c	0.26	+2.2
2,701,802	-		Rv2404c	0.26	+3.2
2,701,802	-		Rv2404c	0.26	+3.0
2,701,984	+		Rv2404c	0.36	+2.1
2,702,122	+		Rv2404c	0.43	+2.6
2,702,122	+		Rv2404c	0.43	+2.6
2,702,122	+		Rv2404c	0.43	+2.0
2,702,339	-		Rv2404c	0.54	+3.0
2,702,483	-		Rv2404c	0.61	+2.1
2,702,509	+		Rv2404c	0.62	+3.1
2,702,851	+		Rv2404c	0.80	+2.6
2,702,852	-		Rv2404c	0.80	+2.8
2,702,896	+		Rv2404c	0.82	+0.9
2,702,896	+		Rv2404c	0.82	+3.7
2,703,092	+				+2.6
2,703,093	-				+2.4
2,703,224	+				+1.2
2,703,310	+				-0.6
2,703,311	-				+0.5
2,703,311	-				-1.5
2,703,489	-		Rv2405	0.39	-0.9
2,703,548	+		Rv2405	0.49	+0.4
2,703,549	-		Rv2405	0.49	+1.2
2,703,549	-		Rv2405	0.49	-0.1
2,703,695	+		Rv2405	0.75	-0.9
2,703,695	+		Rv2405	0.75	-1.3
2,703,717	+		Rv2405	0.79	-0.1
2,703,825	-				-0.9
2,704,025	+				+0.2
2,704,025	+				-1.0
2,704,025	+				+1.4
2,704,025	+				+0.7
2,704,092	+		Rv2406c	0.19	-0.3
2,704,092	+		Rv2406c	0.19	+0.1
2,704,215	+		Rv2406c	0.48	-0.9
2,704,216	-		Rv2406c	0.48	-0.2
2,704,216	-		Rv2406c	0.48	-0.8
2,704,216	-		Rv2406c	0.48	-0.8