Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2401

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,697,090	+		Rv2400c	0.42	+2.2
2,697,651	+				+0.2
2,698,043	+				+2.2
2,698,248	+				+0.1
2,698,248	+				+1.7
2,698,249	-				+0.2
2,698,287	-				+0.3
2,698,287	-				+0.2
2,698,330	+				-0.3
2,698,331	-				+0.2
2,698,536	+				+0.3
2,698,840	+		Rv2402	0.16	-1.0
2,698,840	+		Rv2402	0.16	+1.2
2,698,983	-		Rv2402	0.24	+0.6
2,699,025	-		Rv2402	0.26	-1.4
2,699,038	-		Rv2402	0.26	+0.9
2,699,038	-		Rv2402	0.26	+0.2
2,699,038	-		Rv2402	0.26	-1.0