Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2395

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,689,168	+		Rv2394	0.60	+0.1
2,689,168	+		Rv2394	0.60	+0.7
2,689,168	+		Rv2394	0.60	+0.8
2,689,169	-		Rv2394	0.60	-0.8
2,689,170	+		Rv2394	0.60	-0.4
2,689,170	+		Rv2394	0.60	+2.8
2,689,170	+		Rv2394	0.60	-0.6
2,689,171	-		Rv2394	0.60	-1.2
2,689,234	+		Rv2394	0.63	-0.1
2,689,234	+		Rv2394	0.63	-0.1
2,689,234	+		Rv2394	0.63	+0.4
2,689,256	+		Rv2394	0.64	-0.3
2,689,372	+		Rv2394	0.70	-0.8
2,689,372	+		Rv2394	0.70	+0.9
2,689,423	+		Rv2394	0.73	+0.8
2,689,489	-		Rv2394	0.77	+0.7
2,689,598	-		Rv2394	0.82	+0.5
2,689,738	-		Rv2394	0.89	+0.4
2,689,831	-				-0.6
2,690,051	+				-0.5
2,690,065	+				+1.5
2,690,137	+				+0.7
2,690,137	+				+0.1
2,690,137	+				+2.4
2,690,137	+				-0.2
2,690,166	-				-0.5
2,690,166	-				+3.6
2,690,175	+				-1.2
2,690,272	+				-0.4
2,690,272	+				+1.3
2,690,273	-		Rv2395	0.10	-0.6
2,690,420	+		Rv2395	0.17	+0.5
2,690,421	-		Rv2395	0.17	-1.0
2,690,421	-		Rv2395	0.17	+0.2
2,690,643	+		Rv2395	0.28	+0.2
2,690,764	-		Rv2395	0.35	+1.7
2,690,811	-		Rv2395	0.37	+1.2
2,690,811	-		Rv2395	0.37	+0.4
2,691,168	-		Rv2395	0.55	-0.4
2,691,261	-		Rv2395	0.59	+1.4
2,691,303	-		Rv2395	0.61	-1.2
2,691,303	-		Rv2395	0.61	+0.2
2,691,303	-		Rv2395	0.61	+1.7
2,691,303	-		Rv2395	0.61	+0.6
2,691,303	-		Rv2395	0.61	-1.0
2,691,313	+		Rv2395	0.62	+0.8
2,691,313	+		Rv2395	0.62	+1.5
2,691,344	-		Rv2395	0.63	-0.3
2,691,571	-		Rv2395	0.75	+1.9
2,691,606	+		Rv2395	0.77	+0.1
2,691,607	-		Rv2395	0.77	+2.2
2,691,607	-		Rv2395	0.77	-0.1
2,691,607	-		Rv2395	0.77	-0.6
2,691,703	+		Rv2395	0.81	+0.1
2,691,703	+		Rv2395	0.81	+2.6
2,691,703	+		Rv2395	0.81	-2.8
2,691,703	+		Rv2395	0.81	+2.2
2,691,703	+		Rv2395	0.81	+0.2
2,691,704	-		Rv2395	0.81	-0.1
2,691,704	-		Rv2395	0.81	-1.1
2,691,704	-		Rv2395	0.81	+0.2
2,691,704	-		Rv2395	0.81	+0.7
2,691,707	+		Rv2395	0.82	+0.8
2,691,707	+		Rv2395	0.82	-0.2
2,691,707	+		Rv2395	0.82	+1.4
2,691,707	+		Rv2395	0.82	+0.3
2,691,707	+		Rv2395	0.82	+0.0
2,691,707	+		Rv2395	0.82	+0.9
2,691,707	+		Rv2395	0.82	+1.7
2,691,708	-		Rv2395	0.82	-0.0
2,691,708	-		Rv2395	0.82	+1.4
2,691,708	-		Rv2395	0.82	+0.4
2,691,708	-		Rv2395	0.82	-0.5
2,691,708	-		Rv2395	0.82	+1.0
2,691,764	+		Rv2395	0.84	+0.9
2,691,764	+		Rv2395	0.84	-0.1
2,691,764	+		Rv2395	0.84	+1.3
2,691,764	+		Rv2395	0.84	+0.2
2,691,765	-		Rv2395	0.84	+0.4
2,691,765	-		Rv2395	0.84	-0.2
2,691,765	-		Rv2395	0.84	-0.5
2,691,765	-		Rv2395	0.84	+2.2
2,691,861	-		Rv2395	0.89	-0.5
2,692,714	-				+1.1
2,692,714	-				+0.3
2,692,714	-				-0.7
2,692,770	+				-0.7
2,692,770	+				-3.1
2,692,771	-				+0.1
2,692,771	-				+0.3
2,692,771	-				-1.9
2,692,771	-				+0.9
2,692,771	-				+2.3
2,692,771	-				+1.0
2,692,848	-				-0.1
2,692,848	-				-0.1
2,692,848	-				-0.1
2,692,848	-				-0.7
2,692,848	-				-0.3
2,692,848	-				+0.8
2,692,982	+		Rv2396	0.17	-2.0
2,692,982	+		Rv2396	0.17	-0.6
2,692,982	+		Rv2396	0.17	-1.5
2,692,983	-		Rv2396	0.17	+1.5
2,693,032	+		Rv2396	0.21	+0.8
2,693,032	+		Rv2396	0.21	+0.4
2,693,033	-		Rv2396	0.22	+0.4
2,693,058	-		Rv2396	0.24	-0.6
2,693,058	-		Rv2396	0.24	-0.7
2,693,058	-		Rv2396	0.24	-0.1
2,693,058	-		Rv2396	0.24	+2.3
2,693,058	-		Rv2396	0.24	-0.2