Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2388c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,681,033	-		Rv2387	0.21	-0.8
2,681,033	-		Rv2387	0.21	-0.6
2,681,033	-		Rv2387	0.21	+1.2
2,681,092	+		Rv2387	0.26	+1.2
2,681,096	-		Rv2387	0.26	+1.2
2,681,133	-		Rv2387	0.29	-1.1
2,681,133	-		Rv2387	0.29	+0.7
2,681,133	-		Rv2387	0.29	-1.0
2,681,133	-		Rv2387	0.29	-0.8
2,681,171	-		Rv2387	0.32	-1.6
2,681,224	+		Rv2387	0.37	-0.1
2,681,225	-		Rv2387	0.37	+0.2
2,681,270	-		Rv2387	0.40	-0.2
2,681,579	+		Rv2387	0.65	+0.3
2,681,621	+		Rv2387	0.68	+0.8
2,681,622	-		Rv2387	0.68	+3.1
2,681,622	-		Rv2387	0.68	-0.2
2,681,771	-		Rv2387	0.80	+1.5
2,681,771	-		Rv2387	0.80	-2.2
2,681,779	-		Rv2387	0.81	-0.9
2,681,803	+		Rv2387	0.83	+1.2
2,681,803	+		Rv2387	0.83	+0.9
2,681,803	+		Rv2387	0.83	+1.2
2,681,803	+		Rv2387	0.83	-0.3
2,681,803	+		Rv2387	0.83	+0.4
2,681,803	+		Rv2387	0.83	-1.2
2,681,803	+		Rv2387	0.83	-0.3
2,681,803	+		Rv2387	0.83	+3.7
2,681,804	-		Rv2387	0.83	+0.8
2,681,804	-		Rv2387	0.83	-0.1
2,681,804	-		Rv2387	0.83	+0.4
2,681,839	+		Rv2387	0.86	+0.4
2,681,839	+		Rv2387	0.86	+1.2
2,681,840	-		Rv2387	0.86	+0.1
2,681,840	-		Rv2387	0.86	+0.2
2,681,840	-		Rv2387	0.86	+0.0
2,681,930	-				-0.5
2,681,957	-				+0.1
2,682,092	-				+0.5
2,682,275	-		Rv2388c	0.23	+1.3
2,682,275	-		Rv2388c	0.23	+1.2
2,682,319	+		Rv2388c	0.27	+0.1
2,682,421	+		Rv2388c	0.36	+0.7
2,682,422	-		Rv2388c	0.36	+0.7
2,682,422	-		Rv2388c	0.36	+0.5
2,682,422	-		Rv2388c	0.36	-0.9
2,682,467	-		Rv2388c	0.40	+0.7
2,682,560	-		Rv2388c	0.48	+1.6
2,682,644	-		Rv2388c	0.56	-0.5
2,682,952	+		Rv2388c	0.83	+0.4
2,682,952	+		Rv2388c	0.83	-0.3
2,682,952	+		Rv2388c	0.83	+0.7
2,682,953	-		Rv2388c	0.83	+0.7
2,682,953	-		Rv2388c	0.83	+0.8
2,682,953	-		Rv2388c	0.83	+0.8
2,683,063	+				+1.3
2,683,064	-				+1.3
2,683,067	+				+1.2
2,683,067	+				+1.2
2,683,067	+				+0.5
2,683,068	-				+0.5
2,683,183	-				+0.2
2,683,210	-				+2.2
2,683,216	+				+0.7
2,683,216	+				+0.2
2,683,216	+				-0.2
2,683,217	-				+1.2
2,683,217	-				-0.4
2,683,340	+		Rv2389c	0.20	+0.1
2,683,340	+		Rv2389c	0.20	+2.2
2,683,341	-		Rv2389c	0.20	-0.2
2,683,349	+		Rv2389c	0.22	+0.2
2,683,349	+		Rv2389c	0.22	-0.4
2,683,349	+		Rv2389c	0.22	-1.0
2,683,350	-		Rv2389c	0.22	+1.7
2,683,385	+		Rv2389c	0.29	+0.3
2,683,385	+		Rv2389c	0.29	+0.3
2,683,385	+		Rv2389c	0.29	+0.4
2,683,385	+		Rv2389c	0.29	-0.6
2,683,386	-		Rv2389c	0.30	+0.6
2,683,386	-		Rv2389c	0.30	-0.4
2,683,386	-		Rv2389c	0.30	-0.1
2,683,489	+		Rv2389c	0.52	+0.5
2,683,490	-		Rv2389c	0.52	-0.2
2,683,492	-		Rv2389c	0.52	+0.5
2,683,647	+		Rv2389c	0.86	+0.7
2,683,648	-		Rv2389c	0.86	-0.2
2,683,648	-		Rv2389c	0.86	-0.3
2,683,648	-		Rv2389c	0.86	-1.6
2,683,691	+				-0.6
2,683,694	+				+1.2
2,683,695	-				+3.8
2,683,695	-				+0.0
2,683,695	-				+0.2
2,683,695	-				+0.4
2,683,695	-				+0.1
2,683,712	+				+0.2
2,683,712	+				-0.6
2,683,712	+				+1.4
2,683,712	+				+1.2
2,683,844	+		Rv2390c	0.24	-0.7
2,683,845	-		Rv2390c	0.24	+0.3
2,683,845	-		Rv2390c	0.24	+2.7
2,683,950	+		Rv2390c	0.43	+1.1
2,683,950	+		Rv2390c	0.43	-0.0
2,683,950	+		Rv2390c	0.43	+0.9
2,683,955	-		Rv2390c	0.44	-0.1
2,684,043	+		Rv2390c	0.60	-0.6
2,684,043	+		Rv2390c	0.60	+0.8
2,684,043	+		Rv2390c	0.60	-0.2
2,684,043	+		Rv2390c	0.60	+1.6
2,684,044	-		Rv2390c	0.60	-0.1
2,684,044	-		Rv2390c	0.60	-1.6
2,684,044	-		Rv2390c	0.60	-0.5
2,684,044	-		Rv2390c	0.60	-0.3