Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2320c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,591,839	-				-1.6
2,591,918	-				+1.5
2,592,288	-		Rv2319c	0.50	-0.4
2,592,479	+		Rv2319c	0.72	-0.1
2,592,480	-		Rv2319c	0.72	+0.6
2,592,480	-		Rv2319c	0.72	-0.1
2,592,671	-				-0.6
2,592,676	+				+1.2
2,592,676	+				-0.6
2,592,677	-				-1.1
2,592,707	+				+0.0
2,592,821	-				+0.4
2,593,001	+		Rv2320c	0.19	-0.2
2,593,153	+		Rv2320c	0.30	-0.7
2,593,153	+		Rv2320c	0.30	+0.2
2,593,154	-		Rv2320c	0.30	-0.6
2,593,154	-		Rv2320c	0.30	-0.0
2,593,154	-		Rv2320c	0.30	-1.2
2,593,154	-		Rv2320c	0.30	-0.6
2,593,327	+		Rv2320c	0.42	-1.0
2,593,328	-		Rv2320c	0.42	-1.0
2,593,328	-		Rv2320c	0.42	-0.6
2,593,432	+		Rv2320c	0.50	-0.2
2,593,433	-		Rv2320c	0.50	-1.2
2,593,433	-		Rv2320c	0.50	-0.3
2,593,627	-		Rv2320c	0.63	-0.0
2,593,696	-		Rv2320c	0.68	-1.3
2,593,744	+		Rv2320c	0.71	-0.5
2,593,744	+		Rv2320c	0.71	+1.6
2,594,008	-		Rv2320c	0.90	+0.2
2,594,155	+				-0.9
2,594,156	-				-0.6
2,594,257	+		Rv2321c	0.19	-0.4