Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2261c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,533,209	-		Rv2259	0.89	-2.0
2,533,305	+				+0.8
2,533,305	+				-1.3
2,533,306	-				+0.7
2,533,868	+		Rv2260	0.85	+0.1
2,534,011	+				+0.6
2,534,012	-				+1.2
2,534,243	-		Rv2261c	0.48	-0.7
2,534,377	-		Rv2261c	0.79	-0.9
2,534,571	-				-0.4
2,534,571	-				-1.5
2,534,603	+		Rv2262c	0.12	-0.0
2,534,603	+		Rv2262c	0.12	-0.7
2,534,648	+		Rv2262c	0.16	-1.2
2,534,649	-		Rv2262c	0.17	-1.1
2,534,649	-		Rv2262c	0.17	-1.3
2,534,875	+		Rv2262c	0.37	-2.5
2,534,927	+		Rv2262c	0.42	+0.4
2,534,928	-		Rv2262c	0.42	-0.3
2,535,025	-		Rv2262c	0.51	+0.1
2,535,082	+		Rv2262c	0.57	+0.3
2,535,330	-		Rv2262c	0.79	+0.4