Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2027c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,271,864	+				-0.3
2,271,864	+				-0.6
2,271,864	+				+1.4
2,271,865	-				-1.4
2,271,865	-				-2.3
2,271,865	-				-0.4
2,272,060	-		Rv2026c	0.22	-1.9
2,272,298	-		Rv2026c	0.49	-1.2
2,273,241	+		Rv2027c	0.26	-0.4
2,273,241	+		Rv2027c	0.26	-0.1
2,273,242	-		Rv2027c	0.26	+0.6
2,273,242	-		Rv2027c	0.26	-1.2
2,273,449	+		Rv2027c	0.38	-1.2
2,273,450	-		Rv2027c	0.39	-0.1
2,273,608	+		Rv2027c	0.48	+1.9
2,273,609	-		Rv2027c	0.48	-1.1
2,273,697	-		Rv2027c	0.53	-1.7
2,273,697	-		Rv2027c	0.53	+0.6
2,273,697	-		Rv2027c	0.53	-0.8
2,274,003	+		Rv2027c	0.71	+1.4
2,274,003	+		Rv2027c	0.71	+0.6
2,274,110	-		Rv2027c	0.77	-0.8
2,274,217	-		Rv2027c	0.83	-0.8
2,274,235	+		Rv2027c	0.84	+2.2
2,274,236	-		Rv2027c	0.84	-1.0
2,274,236	-		Rv2027c	0.84	+2.2
2,274,236	-		Rv2027c	0.84	-0.5
2,274,236	-		Rv2027c	0.84	+0.4
2,274,236	-		Rv2027c	0.84	+0.2
2,274,244	-		Rv2027c	0.85	-2.1
2,274,296	-		Rv2027c	0.88	-0.8
2,274,510	+				-1.5
2,274,511	-				-0.7
2,274,511	-				-2.6
2,274,511	-				-0.1
2,274,511	-				+0.4
2,274,511	-				-0.6
2,274,514	+				+0.0
2,274,514	+				-1.4
2,274,514	+				+0.0
2,274,514	+				+1.5
2,274,515	-				-0.7
2,274,515	-				-0.3
2,274,515	-				+0.1
2,274,515	-				-1.7
2,274,515	-				+0.0
2,274,515	-				-3.1
2,274,515	-				-0.1
2,274,693	-		Rv2028c	0.15	+2.2
2,274,718	-		Rv2028c	0.18	-0.2
2,275,037	-		Rv2028c	0.56	-1.5
2,275,370	-				-0.8
2,275,445	+				-1.3
2,275,446	-				-0.8