Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1995

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,237,295	+				+2.2
2,237,295	+				-0.6
2,237,296	-				-0.3
2,237,559	-				-0.5
2,237,559	-				-0.7
2,237,559	-				+3.2
2,237,559	-				-0.9
2,237,559	-				-0.6
2,237,569	+				+0.3
2,237,569	+				+1.9
2,237,570	-				-0.2
2,237,570	-				-0.1
2,237,633	+				-0.5
2,237,634	-				-1.5
2,237,634	-				-0.3
2,237,782	+		Rv1994c	0.43	+3.0
2,237,782	+		Rv1994c	0.43	+0.2
2,237,782	+		Rv1994c	0.43	-1.1
2,237,783	-		Rv1994c	0.43	+3.2
2,237,783	-		Rv1994c	0.43	-0.2
2,237,865	+		Rv1994c	0.66	-2.5
2,237,866	-		Rv1994c	0.67	-0.6
2,238,049	-				-0.1
2,238,269	+		Rv1995	0.17	-0.3
2,238,489	+		Rv1995	0.45	-1.1
2,238,489	+		Rv1995	0.45	-1.2
2,238,489	+		Rv1995	0.45	+0.8
2,238,490	-		Rv1995	0.45	+0.6
2,238,490	-		Rv1995	0.45	-0.6
2,238,490	-		Rv1995	0.45	-0.6
2,238,513	+		Rv1995	0.48	-0.5
2,238,513	+		Rv1995	0.48	-0.3
2,238,513	+		Rv1995	0.48	-0.9
2,238,513	+		Rv1995	0.48	-0.5
2,238,513	+		Rv1995	0.48	-1.6
2,238,513	+		Rv1995	0.48	+0.4
2,238,513	+		Rv1995	0.48	-0.4
2,238,513	+		Rv1995	0.48	-0.3
2,238,514	-		Rv1995	0.49	+3.0
2,238,514	-		Rv1995	0.49	-0.4
2,238,514	-		Rv1995	0.49	+0.7
2,238,514	-		Rv1995	0.49	-0.3
2,238,684	+		Rv1995	0.71	+1.7
2,238,684	+		Rv1995	0.71	+0.2
2,238,684	+		Rv1995	0.71	+1.7
2,238,684	+		Rv1995	0.71	+1.6
2,238,684	+		Rv1995	0.71	-0.8
2,238,685	-		Rv1995	0.71	-0.8
2,238,685	-		Rv1995	0.71	-0.7
2,238,880	-				-0.4
2,238,880	-				+0.3
2,238,906	+				+0.5
2,238,907	-				-0.8
2,238,915	+				+1.1
2,238,977	+				+0.1
2,238,978	-				-1.5
2,238,980	+				-0.0
2,238,980	+				-0.4
2,238,981	-				-0.4
2,238,981	-				+0.1
2,239,066	+				-0.2
2,239,146	+		Rv1996	0.15	-0.8
2,239,146	+		Rv1996	0.15	-0.5
2,239,147	-		Rv1996	0.15	-0.5
2,239,147	-		Rv1996	0.15	-0.6
2,239,147	-		Rv1996	0.15	-0.9
2,239,176	-		Rv1996	0.18	-0.4
2,239,176	-		Rv1996	0.18	-0.7
2,239,176	-		Rv1996	0.18	+0.9
2,239,223	+		Rv1996	0.23	-0.2
2,239,224	-		Rv1996	0.23	-0.8
2,239,336	-		Rv1996	0.35	-0.9
2,239,336	-		Rv1996	0.35	-0.7
2,239,476	+		Rv1996	0.49	-1.1
2,239,476	+		Rv1996	0.49	-0.4
2,239,476	+		Rv1996	0.49	-0.6
2,239,649	-		Rv1996	0.68	-1.1