Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1904

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,150,015	+		Rv1902c	0.80	-0.3
2,150,016	-		Rv1902c	0.80	-1.0
2,150,016	-		Rv1902c	0.80	-0.8
2,150,171	+				+0.2
2,150,172	-				-1.1
2,150,192	+				-0.6
2,150,193	-				-1.2
2,150,232	+				-0.8
2,150,559	+		Rv1903	0.48	-1.7
2,150,559	+		Rv1903	0.48	+0.6
2,150,559	+		Rv1903	0.48	+0.2
2,150,559	+		Rv1903	0.48	-1.0
2,150,560	-		Rv1903	0.48	+1.4
2,150,560	-		Rv1903	0.48	-0.9
2,150,587	+		Rv1903	0.55	-1.1
2,150,587	+		Rv1903	0.55	+0.7
2,150,588	-		Rv1903	0.55	+3.2
2,150,588	-		Rv1903	0.55	-0.4
2,150,615	+		Rv1903	0.62	+0.2
2,150,766	+				+1.2
2,150,767	-				-1.3
2,150,767	-				-1.5
2,150,767	-				-1.4
2,150,797	+				+0.4
2,150,797	+				-1.1
2,150,798	-				-1.0
2,150,798	-				-1.0
2,150,798	-				+0.5
2,150,821	+				-1.0
2,150,822	-				-0.7
2,150,822	-				-1.0
2,150,822	-				-1.1
2,150,822	-				-0.8
2,150,827	+				-0.7
2,150,827	+				+2.2
2,150,905	+				-0.1
2,150,925	-				-0.6
2,150,925	-				-1.7
2,151,029	-		Rv1904	0.17	-0.9
2,151,212	+		Rv1904	0.60	-0.9
2,151,212	+		Rv1904	0.60	-0.6
2,151,212	+		Rv1904	0.60	-1.7
2,151,212	+		Rv1904	0.60	-0.1
2,151,213	-		Rv1904	0.60	-0.4
2,151,213	-		Rv1904	0.60	-0.8
2,151,213	-		Rv1904	0.60	-0.4
2,151,213	-		Rv1904	0.60	-0.1
2,151,262	+		Rv1904	0.71	+0.2
2,151,262	+		Rv1904	0.71	-1.6
2,151,263	-		Rv1904	0.72	+1.7
2,151,263	-		Rv1904	0.72	-1.2
2,151,327	+		Rv1904	0.86	-0.9
2,151,328	-		Rv1904	0.87	-0.6
2,151,338	+		Rv1904	0.89	-0.0
2,151,338	+		Rv1904	0.89	-0.2
2,151,510	-				-0.4
2,151,625	+		Rv1905c	0.20	-0.4
2,151,625	+		Rv1905c	0.20	+1.2
2,151,626	-		Rv1905c	0.20	+0.6
2,151,626	-		Rv1905c	0.20	-0.8
2,151,626	-		Rv1905c	0.20	+0.3
2,151,626	-		Rv1905c	0.20	-0.7
2,151,626	-		Rv1905c	0.20	+1.0
2,151,659	-		Rv1905c	0.23	+0.2
2,151,696	+		Rv1905c	0.27	+0.2
2,151,697	-		Rv1905c	0.27	+1.1
2,151,697	-		Rv1905c	0.27	+1.2
2,151,716	-		Rv1905c	0.29	-0.5
2,151,716	-		Rv1905c	0.29	-0.2
2,151,738	-		Rv1905c	0.32	-1.2
2,151,883	+		Rv1905c	0.47	-0.7
2,151,883	+		Rv1905c	0.47	-0.2
2,151,884	-		Rv1905c	0.47	-1.0
2,151,920	-		Rv1905c	0.51	+1.7
2,151,990	+		Rv1905c	0.58	-0.8
2,151,990	+		Rv1905c	0.58	-0.6
2,151,990	+		Rv1905c	0.58	-0.3
2,152,110	+		Rv1905c	0.70	-0.3
2,152,210	+		Rv1905c	0.81	-0.2
2,152,211	-		Rv1905c	0.81	-1.1
2,152,330	+				+1.2
2,152,330	+				-0.2
2,152,331	-				+0.2