Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1746

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,971,145	+		Rv1744c	0.39	-0.8
1,971,145	+		Rv1744c	0.39	+0.4
1,971,145	+		Rv1744c	0.39	-0.8
1,971,145	+		Rv1744c	0.39	-0.4
1,971,146	-		Rv1744c	0.39	-1.7
1,971,146	-		Rv1744c	0.39	-0.9
1,971,146	-		Rv1744c	0.39	-1.2
1,971,146	-		Rv1744c	0.39	+0.0
1,971,181	+		Rv1744c	0.48	-1.2
1,971,182	-		Rv1744c	0.48	-0.5
1,971,182	-		Rv1744c	0.48	+2.2
1,971,182	-		Rv1744c	0.48	-1.8
1,971,182	-		Rv1744c	0.48	-1.1
1,971,182	-		Rv1744c	0.48	+0.2
1,971,203	-		Rv1744c	0.53	-0.4
1,971,381	+				-2.8
1,971,381	+				-0.7
1,971,382	-				-1.0
1,971,382	-				-2.1
1,971,385	+				+1.5
1,971,385	+				-1.7
1,971,385	+				-1.1
1,971,386	-				-2.2
1,971,386	-				-1.2
1,971,386	-				-0.5
1,971,462	+		Rv1745c	0.13	-0.9
1,971,607	-		Rv1745c	0.37	-0.9
1,971,647	-		Rv1745c	0.44	-1.6
1,971,856	-		Rv1745c	0.78	-0.5
1,971,856	-		Rv1745c	0.78	-1.9
1,972,005	-				-2.1
1,972,127	-				-0.5
1,972,127	-				-0.2
1,972,217	-				-0.5
1,972,263	-				-0.3
1,972,263	-				+0.6
1,972,263	-				-1.0
1,972,263	-				-0.6
1,972,294	+		Rv1746	0.11	+0.3
1,972,430	+		Rv1746	0.20	-1.1
1,972,431	-		Rv1746	0.20	-1.1
1,972,516	+		Rv1746	0.26	-0.6
1,972,517	-		Rv1746	0.26	-1.3
1,972,707	+		Rv1746	0.40	-0.5
1,972,708	-		Rv1746	0.40	-0.6
1,972,742	-		Rv1746	0.42	-1.0
1,973,359	+		Rv1746	0.85	-0.4
1,973,359	+		Rv1746	0.85	-1.3
1,973,623	-				-2.2
1,973,675	+				-0.6
1,973,843	+				-0.4
1,973,843	+				-1.7
1,973,844	-				-0.6
1,973,879	+				-1.6
1,973,879	+				-0.0
1,973,879	+				+0.7
1,973,879	+				-1.3
1,973,880	-				+0.6
1,973,880	-				-0.3
1,973,880	-				-1.0
1,973,986	-		Rv1747	0.14	+1.0