Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1742

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,967,213	+		Rv1739c	0.75	-1.4
1,967,213	+		Rv1739c	0.75	-0.8
1,967,286	+		Rv1739c	0.79	-0.8
1,967,327	+		Rv1739c	0.82	-0.7
1,967,435	+		Rv1739c	0.88	-0.1
1,967,501	+				-0.1
1,967,501	+				-0.3
1,967,579	+				-0.2
1,967,657	+				-1.4
1,967,672	+				-0.4
1,967,692	+				-0.2
1,967,693	-				+0.6
1,967,751	+		Rv1740	0.22	-0.9
1,967,985	-		Rv1741	0.27	+1.7
1,968,112	+		Rv1741	0.78	-0.7
1,968,114	+		Rv1741	0.79	-1.4
1,968,135	+		Rv1741	0.88	-0.4
1,968,136	-		Rv1741	0.88	-1.2
1,968,141	+				-0.8
1,968,518	+		Rv1742	0.47	-0.7
1,968,519	-		Rv1742	0.47	-0.7
1,968,545	+		Rv1742	0.50	+1.2
1,968,561	-		Rv1742	0.53	-1.9
1,968,689	+		Rv1742	0.70	-1.4
1,968,690	-		Rv1742	0.70	-1.1
1,968,690	-		Rv1742	0.70	+1.0
1,968,768	-		Rv1742	0.81	-2.4
1,968,870	+				-0.4
1,968,871	-				-0.2
1,968,908	+				-1.4
1,968,909	-				-0.7
1,968,959	+				-0.8
1,968,959	+				-1.4
1,968,960	-				-0.6
1,969,033	+				-0.5
1,969,094	+				-1.4
1,969,094	+				+0.4
1,969,094	+				-2.1
1,969,094	+				-1.8
1,969,183	+		Rv1743	0.11	-0.7
1,969,183	+		Rv1743	0.11	-0.7
1,969,184	-		Rv1743	0.11	-1.5
1,969,271	+		Rv1743	0.16	-0.8
1,969,272	-		Rv1743	0.16	-0.6
1,969,272	-		Rv1743	0.16	+2.2
1,969,464	-		Rv1743	0.27	-1.1
1,969,541	+		Rv1743	0.32	-0.7
1,969,544	+		Rv1743	0.32	+0.6
1,969,544	+		Rv1743	0.32	-0.4
1,969,545	-		Rv1743	0.32	-0.8
1,969,545	-		Rv1743	0.32	-0.6
1,969,584	-		Rv1743	0.34	-1.0
1,969,620	-		Rv1743	0.36	-1.1
1,969,646	+		Rv1743	0.38	-0.4
1,969,785	-		Rv1743	0.46	-0.9
1,969,785	-		Rv1743	0.46	+0.3