Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1690 and Rv1691 are separated by 38 nucleotides Rv1691 and Rv1692 overlap by 4 nucleotides Rv1692 and Rv1693 overlap by 4 nucleotides Rv1693 and Rv1694 are separated by 7 nucleotides Rv1694 and Rv1695 overlap by 1 nucleotides
Rv1690: Rv1690 - Probable lipoprotein LprJ, at 1,915,527 to 1,915,910
Rv1690
Rv1691: Rv1691 - Conserved hypothetical protein, at 1,915,949 to 1,916,701
Rv1691
Rv1692: Rv1692 - Probable phosphatase, at 1,916,698 to 1,917,759
Rv1692
Rv1693: Rv1693 - Conserved hypothetical protein, at 1,917,756 to 1,917,932
Rv1693
Rv1694: Rv1694 - 2'-O-methyltransferase TlyA, at 1,917,940 to 1,918,746
Rv1694
Rv1695: Rv1695 - Inorganic polyphosphate/ATP-NAD kinase PpnK (poly(P)/ATP NAD kinase), at 1,918,746 to 1,919,669
Rv1695
Position (kb) 1916
1917
1918 Strain fitness (log2 ratio) -3
-2
-1
0
1 at 1915.832 kb on + strand, within Rv1690 at 1915.833 kb on - strand, within Rv1690 at 1915.915 kb on + strand at 1916.137 kb on - strand, within Rv1691 at 1916.139 kb on + strand, within Rv1691 at 1916.619 kb on + strand, within Rv1691 at 1916.679 kb on + strand at 1916.844 kb on + strand, within Rv1692 at 1917.415 kb on + strand, within Rv1692 at 1917.442 kb on + strand, within Rv1692 at 1917.442 kb on + strand, within Rv1692 at 1917.442 kb on + strand, within Rv1692 at 1917.443 kb on - strand, within Rv1692 at 1917.742 kb on - strand at 1917.742 kb on - strand at 1917.747 kb on - strand at 1917.747 kb on - strand at 1917.799 kb on + strand, within Rv1693 at 1917.800 kb on - strand, within Rv1693 at 1918.148 kb on + strand, within Rv1694 at 1918.654 kb on + strand, within Rv1694
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 1,915,832 + Rv1690 0.79 -0.6 1,915,833 - Rv1690 0.80 +0.6 1,915,915 + -1.0 1,916,137 - Rv1691 0.25 -1.0 1,916,139 + Rv1691 0.25 -2.9 1,916,619 + Rv1691 0.89 -0.9 1,916,679 + +1.2 1,916,844 + Rv1692 0.14 +0.8 1,917,415 + Rv1692 0.68 +0.6 1,917,442 + Rv1692 0.70 +0.2 1,917,442 + Rv1692 0.70 +1.6 1,917,442 + Rv1692 0.70 -1.0 1,917,443 - Rv1692 0.70 -0.8 1,917,742 - +1.0 1,917,742 - -0.9 1,917,747 - -0.4 1,917,747 - -1.3 1,917,799 + Rv1693 0.24 -1.8 1,917,800 - Rv1693 0.25 -0.6 1,918,148 + Rv1694 0.26 +0.4 1,918,654 + Rv1694 0.88 -0.9
Or see this region's nucleotide sequence