Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1634

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,838,168	-		Rv1633	0.52	-0.1
1,838,248	+		Rv1633	0.56	+0.5
1,838,248	+		Rv1633	0.56	-1.1
1,838,248	+		Rv1633	0.56	+0.2
1,838,249	-		Rv1633	0.56	-1.3
1,838,566	+		Rv1633	0.71	+0.0
1,838,567	-		Rv1633	0.71	-1.1
1,838,567	-		Rv1633	0.71	+1.2
1,838,734	+		Rv1633	0.79	-0.3
1,838,734	+		Rv1633	0.79	-0.0
1,838,734	+		Rv1633	0.79	-0.3
1,838,735	-		Rv1633	0.79	-0.9
1,838,735	-		Rv1633	0.79	+0.6
1,838,810	-		Rv1633	0.83	-0.2
1,838,810	-		Rv1633	0.83	+0.1
1,839,038	+				+0.1
1,839,039	-				+3.2
1,839,039	-				-2.5
1,839,208	+				-1.1
1,839,219	+				-0.3
1,839,219	+				-0.1
1,839,262	-				-1.6
1,839,334	-		Rv1634	0.12	-0.8
1,839,334	-		Rv1634	0.12	+0.0
1,839,334	-		Rv1634	0.12	+2.2
1,839,354	+		Rv1634	0.13	-0.2
1,839,392	+		Rv1634	0.16	+0.6
1,839,393	-		Rv1634	0.16	-2.0
1,839,426	+		Rv1634	0.18	+0.9
1,839,427	-		Rv1634	0.18	+0.2
1,839,427	-		Rv1634	0.18	+1.2
1,839,466	+		Rv1634	0.21	-0.2
1,839,466	+		Rv1634	0.21	+0.6
1,839,466	+		Rv1634	0.21	+1.9
1,839,467	-		Rv1634	0.21	-0.8
1,839,523	+		Rv1634	0.25	-0.0
1,839,547	+		Rv1634	0.27	+1.2
1,839,547	+		Rv1634	0.27	-0.8
1,839,553	-		Rv1634	0.27	+0.2
1,839,821	-		Rv1634	0.46	+1.7
1,839,976	+		Rv1634	0.57	+0.2
1,839,976	+		Rv1634	0.57	+0.4
1,839,976	+		Rv1634	0.57	-0.4
1,839,977	-		Rv1634	0.57	-0.7
1,840,006	-		Rv1634	0.59	-0.4
1,840,046	+		Rv1634	0.62	+0.1
1,840,050	+		Rv1634	0.62	-0.4
1,840,050	+		Rv1634	0.62	+1.2
1,840,050	+		Rv1634	0.62	+0.2
1,840,050	+		Rv1634	0.62	+0.8
1,840,050	+		Rv1634	0.62	-0.1
1,840,050	+		Rv1634	0.62	-1.7
1,840,050	+		Rv1634	0.62	+0.7
1,840,050	+		Rv1634	0.62	-1.2
1,840,050	+		Rv1634	0.62	-0.3
1,840,051	-		Rv1634	0.62	+0.9
1,840,178	+		Rv1634	0.71	-0.4
1,840,349	+		Rv1634	0.83	-1.2
1,840,408	+		Rv1634	0.88	+0.2
1,840,409	-		Rv1634	0.88	+3.8
1,840,409	-		Rv1634	0.88	+0.1
1,840,498	+				-0.3
1,840,500	+				-0.6
1,840,500	+				+1.6
1,840,500	+				-2.1
1,840,500	+				+0.5
1,840,500	+				-1.1
1,840,501	-				+0.6
1,840,501	-				+0.6
1,840,501	-				+0.5
1,840,501	-				+0.2
1,840,501	-				-0.9
1,840,501	-				+0.7
1,840,501	-				+0.0
1,840,501	-				+0.1
1,840,501	-				-0.6
1,840,501	-				-1.3
1,840,546	-				+0.2
1,840,600	+				-0.6
1,840,600	+				-0.4
1,840,601	-				-1.5
1,840,640	-				-3.6
1,840,640	-				-0.5
1,840,655	-				-1.1
1,840,655	-				-0.9
1,840,656	+				+0.2
1,840,656	+				-2.0
1,840,779	-		Rv1635c	0.12	+0.6
1,840,828	+		Rv1635c	0.15	-1.2
1,840,828	+		Rv1635c	0.15	-1.9
1,840,829	-		Rv1635c	0.15	-1.5
1,840,829	-		Rv1635c	0.15	-2.7
1,840,984	+		Rv1635c	0.25	-1.0
1,840,985	-		Rv1635c	0.25	-1.3
1,841,006	-		Rv1635c	0.26	-0.7
1,841,029	+		Rv1635c	0.27	-1.4
1,841,161	+		Rv1635c	0.35	+2.8
1,841,162	-		Rv1635c	0.35	-1.0
1,841,164	+		Rv1635c	0.35	-1.0
1,841,188	+		Rv1635c	0.37	-0.3
1,841,252	+		Rv1635c	0.41	+0.7
1,841,351	-		Rv1635c	0.47	-0.2
1,841,351	-		Rv1635c	0.47	+0.8
1,841,361	+		Rv1635c	0.47	-0.8
1,841,362	-		Rv1635c	0.47	+0.2
1,841,362	-		Rv1635c	0.47	-0.7
1,841,362	-		Rv1635c	0.47	-1.3
1,841,362	-		Rv1635c	0.47	-1.7
1,841,436	+		Rv1635c	0.52	-0.4
1,841,436	+		Rv1635c	0.52	+0.6
1,841,437	-		Rv1635c	0.52	-0.7
1,841,437	-		Rv1635c	0.52	-1.6
1,841,437	-		Rv1635c	0.52	+0.4
1,841,543	-		Rv1635c	0.58	-2.6
1,841,543	-		Rv1635c	0.58	-1.3
1,841,543	-		Rv1635c	0.58	-0.5
1,841,570	+		Rv1635c	0.60	-1.1