Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1472

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,658,934	+				+3.2
1,658,935	-				-0.4
1,659,008	-				-1.0
1,659,097	+		Rv1470	0.31	-0.3
1,659,097	+		Rv1470	0.31	-0.0
1,659,098	-		Rv1470	0.31	-0.8
1,659,296	-		Rv1470	0.84	-1.4
1,659,296	-		Rv1470	0.84	+0.9
1,659,296	-		Rv1470	0.84	+0.4
1,659,296	-		Rv1470	0.84	+0.1
1,659,296	-		Rv1470	0.84	+0.4
1,659,296	-		Rv1470	0.84	+2.9
1,659,941	-		Rv1472	0.21	+0.2
1,660,057	+		Rv1472	0.34	-1.2
1,660,057	+		Rv1472	0.34	-0.1
1,660,057	+		Rv1472	0.34	+0.4
1,660,058	-		Rv1472	0.34	-0.7
1,660,058	-		Rv1472	0.34	+0.3
1,660,097	+		Rv1472	0.39	+0.6
1,660,204	-		Rv1472	0.51	-0.5
1,660,394	+		Rv1472	0.74	-0.7
1,660,464	+		Rv1472	0.82	-0.7
1,660,465	-		Rv1472	0.82	-1.9
1,660,465	-		Rv1472	0.82	+0.2
1,660,465	-		Rv1472	0.82	-1.0
1,660,563	-				-1.0
1,660,618	+				+1.0
1,660,618	+				-0.5
1,660,618	+				-1.6
1,660,668	-				+0.8
1,660,766	+				+1.2
1,660,766	+				+0.6
1,660,822	-		Rv1473	0.10	-0.1
1,661,354	+		Rv1473	0.43	+1.2