Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1100

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,227,867	-		Rv1099c	0.25	-0.6
1,228,243	-		Rv1099c	0.59	+0.6
1,228,914	+		Rv1100	0.33	-2.1
1,228,915	-		Rv1100	0.33	-2.6
1,228,915	-		Rv1100	0.33	-0.7
1,229,110	-		Rv1100	0.61	-0.8
1,229,110	-		Rv1100	0.61	-1.2
1,229,175	+		Rv1100	0.70	-1.0
1,229,503	+				+0.1
1,229,504	-				-0.8
1,229,515	+		Rv1101c	0.11	-0.6
1,229,567	+		Rv1101c	0.15	-0.5
1,229,567	+		Rv1101c	0.15	+0.3
1,229,591	+		Rv1101c	0.17	+0.1
1,229,682	-		Rv1101c	0.25	+1.1
1,229,682	-		Rv1101c	0.25	-0.9
1,229,851	+		Rv1101c	0.40	-0.6
1,229,851	+		Rv1101c	0.40	-0.5
1,229,945	-		Rv1101c	0.48	-0.4
1,229,945	-		Rv1101c	0.48	+0.1
1,229,997	+		Rv1101c	0.52	-0.3
1,229,997	+		Rv1101c	0.52	-1.0
1,229,997	+		Rv1101c	0.52	-0.4
1,229,998	-		Rv1101c	0.52	-0.7
1,230,034	+		Rv1101c	0.56	-0.4
1,230,034	+		Rv1101c	0.56	-2.2
1,230,035	-		Rv1101c	0.56	-0.6
1,230,035	-		Rv1101c	0.56	-0.2
1,230,035	-		Rv1101c	0.56	+2.2
1,230,035	-		Rv1101c	0.56	+0.2
1,230,161	+		Rv1101c	0.66	+0.2
1,230,162	-		Rv1101c	0.67	+0.9