Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1000c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,115,879	+		Rv0999	0.15	+1.2
1,115,999	+		Rv0999	0.31	+1.2
1,115,999	-		Rv0999	0.31	+1.2
1,116,296	+		Rv0999	0.70	+0.7
1,116,297	-		Rv0999	0.70	+0.7
1,116,383	-		Rv0999	0.81	+2.2
1,116,388	+		Rv0999	0.82	+0.2
1,116,389	-		Rv0999	0.82	-0.1
1,116,497	+				+0.1
1,116,532	+				-0.5
1,116,642	+		Rv1000c	0.18	-0.3
1,116,643	-		Rv1000c	0.18	-2.0
1,116,741	-		Rv1000c	0.34	-0.8
1,116,809	-		Rv1000c	0.45	-0.8
1,116,811	+		Rv1000c	0.45	+0.7
1,116,812	-		Rv1000c	0.45	-0.7
1,116,856	+		Rv1000c	0.53	+0.1
1,116,856	+		Rv1000c	0.53	-0.5
1,116,857	-		Rv1000c	0.53	+0.8
1,116,964	+		Rv1000c	0.70	-0.0
1,116,965	-		Rv1000c	0.70	-0.8
1,116,965	-		Rv1000c	0.70	-0.1
1,117,225	+				+1.7
1,117,226	-				-1.0
1,117,414	+		Rv1001	0.19	+0.7
1,117,515	-		Rv1001	0.27	+2.2
1,117,613	+		Rv1001	0.35	-0.9
1,117,721	-		Rv1001	0.44	-1.1
1,117,761	+		Rv1001	0.48	-0.9
1,117,761	+		Rv1001	0.48	-1.1
1,117,762	-		Rv1001	0.48	+0.2
1,117,762	-		Rv1001	0.48	+2.2
1,117,762	-		Rv1001	0.48	-0.9
1,117,762	-		Rv1001	0.48	+0.7
1,117,762	-		Rv1001	0.48	-1.6
1,117,800	+		Rv1001	0.51	-0.8
1,118,021	+		Rv1001	0.69	-0.6
1,118,022	-		Rv1001	0.69	-1.9