Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0890c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0889c and Rv0890c are separated by 86 nucleotidesRv0890c and Rv0891c are separated by 1 nucleotides Rv0889c: Rv0889c - Probable citrate synthase II CitA, at 988,740 to 989,861 Rv0889c Rv0890c: Rv0890c - Probable transcriptional regulatory protein (probably LuxR-family), at 989,948 to 992,596 Rv0890c Rv0891c: Rv0891c - Possible transcriptional regulatory protein, at 992,598 to 993,455 Rv0891c Position (kb) 989 990 991 992 993Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2 3at 989.104 kb on + strand, within Rv0889cat 989.470 kb on + strand, within Rv0889cat 989.470 kb on + strand, within Rv0889cat 989.498 kb on - strand, within Rv0889cat 989.733 kb on + strand, within Rv0889cat 989.862 kb on - strandat 989.898 kb on - strandat 989.982 kb on - strandat 989.982 kb on - strandat 989.990 kb on + strandat 990.189 kb on + strandat 990.189 kb on + strandat 990.189 kb on + strandat 990.189 kb on + strandat 990.190 kb on - strandat 990.438 kb on + strand, within Rv0890cat 990.677 kb on - strand, within Rv0890cat 990.744 kb on + strand, within Rv0890cat 990.744 kb on + strand, within Rv0890cat 990.744 kb on + strand, within Rv0890cat 990.744 kb on + strand, within Rv0890cat 990.745 kb on - strand, within Rv0890cat 990.745 kb on - strand, within Rv0890cat 990.774 kb on + strand, within Rv0890cat 990.774 kb on + strand, within Rv0890cat 990.819 kb on - strand, within Rv0890cat 990.846 kb on + strand, within Rv0890cat 990.868 kb on + strand, within Rv0890cat 990.868 kb on + strand, within Rv0890cat 990.868 kb on + strand, within Rv0890cat 990.868 kb on + strand, within Rv0890cat 990.868 kb on + strand, within Rv0890cat 990.868 kb on + strand, within Rv0890cat 990.868 kb on + strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.869 kb on - strand, within Rv0890cat 990.870 kb on + strand, within Rv0890cat 990.870 kb on + strand, within Rv0890cat 990.870 kb on + strand, within Rv0890cat 990.870 kb on + strand, within Rv0890cat 990.870 kb on + strand, within Rv0890cat 990.871 kb on - strand, within Rv0890cat 990.872 kb on + strand, within Rv0890cat 990.872 kb on + strand, within Rv0890cat 990.872 kb on + strand, within Rv0890cat 990.872 kb on + strand, within Rv0890cat 990.873 kb on - strand, within Rv0890cat 990.873 kb on - strand, within Rv0890cat 990.873 kb on - strand, within Rv0890cat 990.983 kb on - strand, within Rv0890cat 991.085 kb on + strand, within Rv0890cat 991.144 kb on + strand, within Rv0890cat 991.177 kb on - strand, within Rv0890cat 991.200 kb on + strand, within Rv0890cat 991.373 kb on + strand, within Rv0890cat 991.635 kb on + strand, within Rv0890cat 991.636 kb on - strand, within Rv0890cat 991.636 kb on - strand, within Rv0890cat 991.636 kb on - strand, within Rv0890cat 991.638 kb on + strand, within Rv0890cat 991.639 kb on - strand, within Rv0890cat 992.082 kb on - strand, within Rv0890cat 992.205 kb on - strand, within Rv0890cat 992.255 kb on + strand, within Rv0890cat 992.285 kb on + strand, within Rv0890cat 992.285 kb on + strand, within Rv0890cat 992.605 kb on - strandat 992.605 kb on - strandat 992.605 kb on - strandat 992.916 kb on + strand, within Rv0891cat 992.917 kb on - strand, within Rv0891cat 992.937 kb on + strand, within Rv0891cat 992.938 kb on - strand, within Rv0891cat 992.938 kb on - strand, within Rv0891cat 992.939 kb on + strand, within Rv0891cat 992.940 kb on - strand, within Rv0891cat 992.940 kb on - strand, within Rv0891cat 992.943 kb on + strand, within Rv0891cat 992.943 kb on + strand, within Rv0891cat 992.943 kb on + strand, within Rv0891cat 993.029 kb on + strand, within Rv0891cat 993.029 kb on + strand, within Rv0891cat 993.030 kb on - strand, within Rv0891cat 993.216 kb on + strand, within Rv0891cat 993.341 kb on + strand, within Rv0891cat 993.342 kb on - strand, within Rv0891cat 993.434 kb on + strandat 993.477 kb on - strandat 993.526 kb on + strandat 993.527 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL
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989,104 + Rv0889c 0.32 +0.9
989,470 + Rv0889c 0.65 +0.2
989,470 + Rv0889c 0.65 +0.3
989,498 - Rv0889c 0.68 +0.6
989,733 + Rv0889c 0.89 -1.1
989,862 - -0.4
989,898 - -0.7
989,982 - -0.7
989,982 - -2.1
989,990 + +0.9
990,189 + +2.3
990,189 + -0.2
990,189 + -0.2
990,189 + -0.9
990,190 - +0.5
990,438 + Rv0890c 0.18 -1.4
990,677 - Rv0890c 0.28 -0.9
990,744 + Rv0890c 0.30 +0.8
990,744 + Rv0890c 0.30 -0.3
990,744 + Rv0890c 0.30 -1.1
990,744 + Rv0890c 0.30 -3.9
990,745 - Rv0890c 0.30 -0.6
990,745 - Rv0890c 0.30 -1.2
990,774 + Rv0890c 0.31 -0.9
990,774 + Rv0890c 0.31 -1.1
990,819 - Rv0890c 0.33 -1.0
990,846 + Rv0890c 0.34 -0.7
990,868 + Rv0890c 0.35 +0.4
990,868 + Rv0890c 0.35 -1.2
990,868 + Rv0890c 0.35 -1.2
990,868 + Rv0890c 0.35 +0.7
990,868 + Rv0890c 0.35 -1.4
990,868 + Rv0890c 0.35 +3.3
990,868 + Rv0890c 0.35 +1.0
990,869 - Rv0890c 0.35 -0.6
990,869 - Rv0890c 0.35 -2.1
990,869 - Rv0890c 0.35 -1.7
990,869 - Rv0890c 0.35 -0.8
990,869 - Rv0890c 0.35 +0.2
990,869 - Rv0890c 0.35 -1.4
990,869 - Rv0890c 0.35 +0.3
990,869 - Rv0890c 0.35 +0.3
990,870 + Rv0890c 0.35 +0.5
990,870 + Rv0890c 0.35 -0.6
990,870 + Rv0890c 0.35 +0.7
990,870 + Rv0890c 0.35 -0.8
990,870 + Rv0890c 0.35 -0.5
990,871 - Rv0890c 0.35 +0.5
990,872 + Rv0890c 0.35 -0.4
990,872 + Rv0890c 0.35 +1.8
990,872 + Rv0890c 0.35 -0.8
990,872 + Rv0890c 0.35 -0.1
990,873 - Rv0890c 0.35 -0.8
990,873 - Rv0890c 0.35 -1.7
990,873 - Rv0890c 0.35 -1.7
990,983 - Rv0890c 0.39 -0.7
991,085 + Rv0890c 0.43 -1.7
991,144 + Rv0890c 0.45 +0.1
991,177 - Rv0890c 0.46 +0.9
991,200 + Rv0890c 0.47 +0.3
991,373 + Rv0890c 0.54 -0.1
991,635 + Rv0890c 0.64 -1.7
991,636 - Rv0890c 0.64 -0.9
991,636 - Rv0890c 0.64 -2.4
991,636 - Rv0890c 0.64 +0.0
991,638 + Rv0890c 0.64 +0.0
991,639 - Rv0890c 0.64 -1.3
992,082 - Rv0890c 0.81 -0.9
992,205 - Rv0890c 0.85 -0.6
992,255 + Rv0890c 0.87 -0.1
992,285 + Rv0890c 0.88 -1.2
992,285 + Rv0890c 0.88 -0.1
992,605 - +1.6
992,605 - -0.6
992,605 - +0.9
992,916 + Rv0891c 0.37 -1.0
992,917 - Rv0891c 0.37 -0.2
992,937 + Rv0891c 0.40 -1.1
992,938 - Rv0891c 0.40 +0.0
992,938 - Rv0891c 0.40 +0.3
992,939 + Rv0891c 0.40 +0.1
992,940 - Rv0891c 0.40 -0.3
992,940 - Rv0891c 0.40 -0.4
992,943 + Rv0891c 0.40 +2.3
992,943 + Rv0891c 0.40 -1.2
992,943 + Rv0891c 0.40 -0.4
993,029 + Rv0891c 0.50 +1.7
993,029 + Rv0891c 0.50 +0.7
993,030 - Rv0891c 0.50 -1.0
993,216 + Rv0891c 0.72 -1.2
993,341 + Rv0891c 0.87 +1.7
993,342 - Rv0891c 0.87 -1.7
993,434 + -2.7
993,477 - +1.3
993,526 + -0.3
993,527 - -0.0

Or see this region's nucleotide sequence