Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0490 and Rv0491 are separated by 227 nucleotides Rv0491 and Rv0492c overlap by 4 nucleotides Rv0492c and Rv0492A overlap by 4 nucleotides Rv0492A and Rv0493c overlap by 4 nucleotides
Rv0490: Rv0490 - Putative two component sensor histidine kinase SenX3, at 579,349 to 580,581
Rv0490
Rv0491: Rv0491 - Two component sensory transduction protein RegX3 (transcriptional regulatory protein) (probably LuxR-family), at 580,809 to 581,492
Rv0491
Rv0492c: Rv0492c - Probable oxidoreductase GMC-type, at 581,489 to 583,378
Rv0492c
Rv0492A: Rv0492A - Hypothetical protein, at 583,375 to 583,704
Rv0492A
Rv0493c: Rv0493c - Conserved protein, at 583,701 to 584,690
Rv0493c
Position (kb) 581
582
583
584 Strain fitness (log2 ratio) -2
-1
0
1
2 at 580.496 kb on - strand at 580.996 kb on + strand, within Rv0491 at 580.996 kb on + strand, within Rv0491 at 580.996 kb on + strand, within Rv0491 at 580.996 kb on + strand, within Rv0491 at 580.996 kb on + strand, within Rv0491 at 580.997 kb on - strand, within Rv0491 at 580.997 kb on - strand, within Rv0491 at 580.997 kb on - strand, within Rv0491 at 580.997 kb on - strand, within Rv0491 at 580.997 kb on - strand, within Rv0491 at 581.100 kb on + strand, within Rv0491 at 581.368 kb on - strand, within Rv0491 at 581.475 kb on + strand at 581.528 kb on + strand at 581.852 kb on + strand, within Rv0492c at 581.852 kb on + strand, within Rv0492c at 581.876 kb on + strand, within Rv0492c at 581.876 kb on + strand, within Rv0492c at 581.877 kb on - strand, within Rv0492c at 581.877 kb on - strand, within Rv0492c at 581.877 kb on - strand, within Rv0492c at 581.883 kb on + strand, within Rv0492c at 581.884 kb on - strand, within Rv0492c at 582.152 kb on - strand, within Rv0492c at 582.312 kb on + strand, within Rv0492c at 582.312 kb on + strand, within Rv0492c at 582.783 kb on + strand, within Rv0492c at 582.783 kb on + strand, within Rv0492c at 582.784 kb on - strand, within Rv0492c at 582.795 kb on + strand, within Rv0492c at 583.042 kb on - strand, within Rv0492c at 583.189 kb on - strand, within Rv0492c at 583.189 kb on - strand, within Rv0492c at 583.260 kb on + strand at 583.261 kb on - strand at 583.348 kb on - strand at 583.408 kb on + strand, within Rv0492A at 583.408 kb on + strand, within Rv0492A at 583.422 kb on - strand, within Rv0492A at 583.571 kb on + strand, within Rv0492A at 583.572 kb on - strand, within Rv0492A at 583.864 kb on + strand, within Rv0493c at 583.865 kb on - strand, within Rv0493c at 583.876 kb on - strand, within Rv0493c at 583.876 kb on - strand, within Rv0493c at 583.876 kb on - strand, within Rv0493c at 584.055 kb on + strand, within Rv0493c at 584.073 kb on + strand, within Rv0493c at 584.091 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.156 kb on - strand, within Rv0493c at 584.156 kb on - strand, within Rv0493c at 584.156 kb on - strand, within Rv0493c at 584.355 kb on - strand, within Rv0493c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 580,496 - -0.1 580,996 + Rv0491 0.27 +0.9 580,996 + Rv0491 0.27 +1.2 580,996 + Rv0491 0.27 -1.2 580,996 + Rv0491 0.27 -1.8 580,996 + Rv0491 0.27 +2.2 580,997 - Rv0491 0.27 -2.2 580,997 - Rv0491 0.27 -0.2 580,997 - Rv0491 0.27 -1.7 580,997 - Rv0491 0.27 -0.8 580,997 - Rv0491 0.27 -0.5 581,100 + Rv0491 0.43 -0.6 581,368 - Rv0491 0.82 -0.3 581,475 + -1.2 581,528 + -1.7 581,852 + Rv0492c 0.19 -1.3 581,852 + Rv0492c 0.19 -0.3 581,876 + Rv0492c 0.20 -1.8 581,876 + Rv0492c 0.20 -1.0 581,877 - Rv0492c 0.21 +0.1 581,877 - Rv0492c 0.21 -0.3 581,877 - Rv0492c 0.21 +0.7 581,883 + Rv0492c 0.21 +0.1 581,884 - Rv0492c 0.21 -0.2 582,152 - Rv0492c 0.35 -0.5 582,312 + Rv0492c 0.44 -1.8 582,312 + Rv0492c 0.44 -0.6 582,783 + Rv0492c 0.68 +0.4 582,783 + Rv0492c 0.68 -0.6 582,784 - Rv0492c 0.69 -0.7 582,795 + Rv0492c 0.69 -1.1 583,042 - Rv0492c 0.82 +0.2 583,189 - Rv0492c 0.90 +0.2 583,189 - Rv0492c 0.90 -0.5 583,260 + -0.1 583,261 - +1.2 583,348 - +2.2 583,408 + Rv0492A 0.10 -0.1 583,408 + Rv0492A 0.10 -0.1 583,422 - Rv0492A 0.14 -1.6 583,571 + Rv0492A 0.59 +1.5 583,572 - Rv0492A 0.60 -1.8 583,864 + Rv0493c 0.16 -1.8 583,865 - Rv0493c 0.17 +2.2 583,876 - Rv0493c 0.18 -0.1 583,876 - Rv0493c 0.18 +0.2 583,876 - Rv0493c 0.18 +0.7 584,055 + Rv0493c 0.36 -0.2 584,073 + Rv0493c 0.38 -0.6 584,091 + Rv0493c 0.39 -1.8 584,155 + Rv0493c 0.46 +0.0 584,155 + Rv0493c 0.46 -1.3 584,155 + Rv0493c 0.46 -1.5 584,155 + Rv0493c 0.46 +0.2 584,155 + Rv0493c 0.46 +0.9 584,156 - Rv0493c 0.46 -1.1 584,156 - Rv0493c 0.46 +0.4 584,156 - Rv0493c 0.46 +0.1 584,355 - Rv0493c 0.66 -1.6
Or see this region's nucleotide sequence