Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0450c and Rv0451c overlap by 4 nucleotides Rv0451c and Rv0452 are separated by 231 nucleotides Rv0452 and Rv0453 are separated by 321 nucleotides
Rv0450c: Rv0450c - Probable conserved transmembrane transport protein MmpL4, at 538,588 to 541,491
Rv0450c
Rv0451c: Rv0451c - Probable conserved membrane protein MmpS4, at 541,488 to 541,910
Rv0451c
Rv0452: Rv0452 - Possible transcriptional regulatory protein, at 542,142 to 542,852
Rv0452
Rv0453: Rv0453 - PPE family protein PPE11, at 543,174 to 544,730
Rv0453
Position (kb) 542
543 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 541.510 kb on + strand at 541.644 kb on - strand, within Rv0451c at 541.801 kb on + strand, within Rv0451c at 541.905 kb on + strand at 541.906 kb on - strand at 541.906 kb on - strand at 541.906 kb on - strand at 541.995 kb on + strand at 541.995 kb on + strand at 542.009 kb on + strand at 542.038 kb on - strand at 542.038 kb on - strand at 542.059 kb on + strand at 542.059 kb on + strand at 542.060 kb on - strand at 542.079 kb on - strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.108 kb on - strand at 542.399 kb on - strand, within Rv0452 at 542.582 kb on - strand, within Rv0452 at 542.658 kb on + strand, within Rv0452 at 542.719 kb on - strand, within Rv0452 at 543.071 kb on + strand at 543.072 kb on - strand at 543.072 kb on - strand at 543.072 kb on - strand at 543.084 kb on + strand at 543.108 kb on + strand at 543.173 kb on + strand at 543.173 kb on + strand at 543.174 kb on - strand at 543.174 kb on - strand at 543.191 kb on - strand at 543.191 kb on - strand at 543.233 kb on + strand at 543.297 kb on + strand at 543.399 kb on + strand, within Rv0453 at 543.577 kb on + strand, within Rv0453 at 543.577 kb on + strand, within Rv0453 at 543.578 kb on - strand, within Rv0453 at 543.604 kb on - strand, within Rv0453 at 543.646 kb on - strand, within Rv0453 at 543.746 kb on + strand, within Rv0453 at 543.747 kb on - strand, within Rv0453
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 541,510 + -1.7 541,644 - Rv0451c 0.37 -0.1 541,801 + Rv0451c 0.74 +0.0 541,905 + +0.2 541,906 - +0.8 541,906 - -0.3 541,906 - +1.1 541,995 + -1.3 541,995 + -1.3 542,009 + +1.7 542,038 - -0.3 542,038 - +3.2 542,059 + +0.9 542,059 + -0.9 542,060 - -0.7 542,079 - -1.3 542,107 + -2.5 542,107 + -0.8 542,107 + -1.0 542,107 + +0.2 542,107 + -0.5 542,107 + +0.4 542,107 + -2.3 542,108 - -0.7 542,399 - Rv0452 0.36 -2.9 542,582 - Rv0452 0.62 -1.5 542,658 + Rv0452 0.73 -1.4 542,719 - Rv0452 0.81 -2.0 543,071 + -0.4 543,072 - +1.2 543,072 - +0.7 543,072 - -0.5 543,084 + -1.4 543,108 + -1.6 543,173 + -1.1 543,173 + +3.0 543,174 - -1.7 543,174 - -0.4 543,191 - -0.2 543,191 - -0.5 543,233 + +0.3 543,297 + -0.4 543,399 + Rv0453 0.14 -0.9 543,577 + Rv0453 0.26 -0.6 543,577 + Rv0453 0.26 -0.4 543,578 - Rv0453 0.26 -0.2 543,604 - Rv0453 0.28 +0.6 543,646 - Rv0453 0.30 -0.2 543,746 + Rv0453 0.37 -0.3 543,747 - Rv0453 0.37 +0.7
Or see this region's nucleotide sequence