Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0419 and Rv0420c overlap by 22 nucleotides Rv0420c and Rv0421c are separated by 160 nucleotides Rv0421c and Rv0422c overlap by 4 nucleotides
Rv0419: Rv0419 - Possible lipoprotein peptidase LpqM, at 505,086 to 506,582
Rv0419
Rv0420c: Rv0420c - Possible transmembrane protein, at 506,561 to 506,971
Rv0420c
Rv0421c: Rv0421c - Conserved hypothetical protein, at 507,132 to 507,761
Rv0421c
Rv0422c: Rv0422c - Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase), at 507,758 to 508,555
Rv0422c
Position (kb) 506
507 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 505.588 kb on - strand, within Rv0419 at 505.664 kb on + strand, within Rv0419 at 505.722 kb on + strand, within Rv0419 at 505.745 kb on + strand, within Rv0419 at 505.745 kb on + strand, within Rv0419 at 505.760 kb on + strand, within Rv0419 at 505.761 kb on - strand, within Rv0419 at 506.149 kb on - strand, within Rv0419 at 506.562 kb on + strand at 506.563 kb on - strand at 506.563 kb on - strand at 506.581 kb on - strand at 506.687 kb on + strand, within Rv0420c at 506.742 kb on + strand, within Rv0420c at 506.743 kb on - strand, within Rv0420c at 506.800 kb on - strand, within Rv0420c at 506.808 kb on + strand, within Rv0420c at 507.051 kb on + strand at 507.051 kb on + strand at 507.067 kb on - strand at 507.098 kb on + strand at 507.139 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 505,588 - Rv0419 0.34 -1.3 505,664 + Rv0419 0.39 -0.8 505,722 + Rv0419 0.42 -0.3 505,745 + Rv0419 0.44 -0.8 505,745 + Rv0419 0.44 -1.1 505,760 + Rv0419 0.45 -2.3 505,761 - Rv0419 0.45 -0.4 506,149 - Rv0419 0.71 -0.9 506,562 + -0.3 506,563 - -2.2 506,563 - -1.3 506,581 - -0.5 506,687 + Rv0420c 0.31 -1.1 506,742 + Rv0420c 0.44 -0.1 506,743 - Rv0420c 0.44 -0.4 506,800 - Rv0420c 0.58 -2.0 506,808 + Rv0420c 0.60 -0.8 507,051 + -0.3 507,051 + -0.5 507,067 - +0.2 507,098 + -3.0 507,139 - +2.2
Or see this region's nucleotide sequence