Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0308 and Rv0309 are separated by 101 nucleotides Rv0309 and Rv0310c are separated by 69 nucleotides Rv0310c and Rv0311 are separated by 23 nucleotides
Rv0308: Rv0308 - Probable conserved integral membrane protein, at 377,113 to 377,829
Rv0308
Rv0309: Rv0309 - Possible conserved exported protein, at 377,931 to 378,587
Rv0309
Rv0310c: Rv0310c - Conserved protein, at 378,657 to 379,148
Rv0310c
Rv0311: Rv0311 - Unknown protein, at 379,172 to 380,401
Rv0311
Position (kb) 378
379
380 Strain fitness (log2 ratio) -1
0
1
2
3 at 377.702 kb on - strand, within Rv0308 at 377.724 kb on - strand, within Rv0308 at 377.886 kb on + strand at 378.106 kb on - strand, within Rv0309 at 378.106 kb on - strand, within Rv0309 at 378.106 kb on - strand, within Rv0309 at 378.278 kb on + strand, within Rv0309 at 379.004 kb on - strand, within Rv0310c at 379.075 kb on + strand, within Rv0310c at 379.081 kb on + strand, within Rv0310c at 379.187 kb on + strand at 379.279 kb on + strand at 379.280 kb on - strand at 379.280 kb on - strand at 379.349 kb on + strand, within Rv0311 at 379.350 kb on - strand, within Rv0311 at 379.544 kb on + strand, within Rv0311 at 379.544 kb on + strand, within Rv0311 at 380.076 kb on + strand, within Rv0311
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 377,702 - Rv0308 0.82 -0.7 377,724 - Rv0308 0.85 -0.6 377,886 + -0.7 378,106 - Rv0309 0.27 +0.3 378,106 - Rv0309 0.27 -1.3 378,106 - Rv0309 0.27 -1.4 378,278 + Rv0309 0.53 -0.2 379,004 - Rv0310c 0.71 +0.5 379,075 + Rv0310c 0.85 +1.9 379,081 + Rv0310c 0.86 +3.3 379,187 + -0.3 379,279 + -1.2 379,280 - +0.6 379,280 - -0.0 379,349 + Rv0311 0.14 +0.5 379,350 - Rv0311 0.14 +0.7 379,544 + Rv0311 0.30 -1.2 379,544 + Rv0311 0.30 +2.3 380,076 + Rv0311 0.73 +1.6
Or see this region's nucleotide sequence