Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0291 and Rv0292 overlap by 4 nucleotides Rv0292 and Rv0293c overlap by 14 nucleotides Rv0293c and Rv0294 are separated by 106 nucleotides Rv0294 and Rv0295c overlap by 12 nucleotides
Rv0291: Rv0291 - Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3), at 354,498 to 355,883
Rv0291
Rv0292: Rv0292 - ESX conserved component EccE3. ESX-3 type VII secretion system protein. Probable transmembrane protein., at 355,880 to 356,875
Rv0292
Rv0293c: Rv0293c - Conserved protein, at 356,862 to 358,064
Rv0293c
Rv0294: Rv0294 - Probable trans-aconitate methyltransferase Tam, at 358,171 to 358,956
Rv0294
Rv0295c: Rv0295c - Conserved protein, at 358,945 to 359,748
Rv0295c
Position (kb) 356
357
358
359 Strain fitness (log2 ratio) -2
-1
0
1
2 at 356.818 kb on + strand at 356.818 kb on + strand at 356.818 kb on + strand at 357.050 kb on + strand, within Rv0293c at 357.050 kb on + strand, within Rv0293c at 357.054 kb on + strand, within Rv0293c at 357.055 kb on - strand, within Rv0293c at 357.085 kb on + strand, within Rv0293c at 357.152 kb on + strand, within Rv0293c at 357.153 kb on - strand, within Rv0293c at 357.153 kb on - strand, within Rv0293c at 357.259 kb on + strand, within Rv0293c at 357.275 kb on + strand, within Rv0293c at 357.275 kb on + strand, within Rv0293c at 357.276 kb on - strand, within Rv0293c at 357.340 kb on + strand, within Rv0293c at 357.340 kb on + strand, within Rv0293c at 357.452 kb on - strand, within Rv0293c at 357.481 kb on + strand, within Rv0293c at 357.517 kb on + strand, within Rv0293c at 357.518 kb on - strand, within Rv0293c at 357.554 kb on + strand, within Rv0293c at 357.555 kb on - strand, within Rv0293c at 357.844 kb on - strand, within Rv0293c at 358.168 kb on + strand at 358.168 kb on + strand at 358.168 kb on + strand at 358.168 kb on + strand at 358.168 kb on + strand at 358.169 kb on - strand at 358.169 kb on - strand at 358.169 kb on - strand at 358.169 kb on - strand at 358.307 kb on - strand, within Rv0294 at 358.619 kb on + strand, within Rv0294 at 358.726 kb on + strand, within Rv0294 at 358.727 kb on - strand, within Rv0294 at 358.884 kb on + strand at 358.885 kb on - strand at 358.955 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 356,818 + +1.5 356,818 + -0.4 356,818 + -0.9 357,050 + Rv0293c 0.16 -0.6 357,050 + Rv0293c 0.16 -0.0 357,054 + Rv0293c 0.16 -2.0 357,055 - Rv0293c 0.16 -0.8 357,085 + Rv0293c 0.19 +1.1 357,152 + Rv0293c 0.24 +0.1 357,153 - Rv0293c 0.24 -0.9 357,153 - Rv0293c 0.24 -1.1 357,259 + Rv0293c 0.33 -0.2 357,275 + Rv0293c 0.34 +1.9 357,275 + Rv0293c 0.34 -0.3 357,276 - Rv0293c 0.34 -0.1 357,340 + Rv0293c 0.40 +0.3 357,340 + Rv0293c 0.40 +0.3 357,452 - Rv0293c 0.49 -1.5 357,481 + Rv0293c 0.51 +1.1 357,517 + Rv0293c 0.54 +0.7 357,518 - Rv0293c 0.55 -0.4 357,554 + Rv0293c 0.58 +0.7 357,555 - Rv0293c 0.58 +0.7 357,844 - Rv0293c 0.82 +0.3 358,168 + -1.1 358,168 + -0.0 358,168 + +0.3 358,168 + -0.8 358,168 + -0.6 358,169 - -0.7 358,169 - +2.3 358,169 - +0.0 358,169 - +1.0 358,307 - Rv0294 0.17 +1.9 358,619 + Rv0294 0.57 -0.7 358,726 + Rv0294 0.71 -0.9 358,727 - Rv0294 0.71 -0.5 358,884 + -1.9 358,885 - -1.2 358,955 - +0.3
Or see this region's nucleotide sequence