Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0246 and Rv0247c overlap by 4 nucleotides Rv0247c and Rv0248c are separated by 0 nucleotides Rv0248c and Rv0249c are separated by 30 nucleotides Rv0249c and Rv0250c are separated by 79 nucleotides
Rv0246: Rv0246 - Probable conserved integral membrane protein, at 296,809 to 298,119
Rv0246
Rv0247c: Rv0247c - Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase), at 298,116 to 298,862
Rv0247c
Rv0248c: Rv0248c - Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase), at 298,863 to 300,803
Rv0248c
Rv0249c: Rv0249c - Probable succinate dehydrogenase [membrane anchor subunit] (succinic dehydrogenase), at 300,834 to 301,655
Rv0249c
Rv0250c: Rv0250c - Conserved protein, at 301,735 to 302,028
Rv0250c
Position (kb) 298
299
300
301 Strain fitness (log2 ratio) -2
-1
0
1
2
3
4 at 298.105 kb on - strand at 298.146 kb on + strand at 298.253 kb on + strand, within Rv0247c at 299.230 kb on - strand, within Rv0248c at 299.240 kb on - strand, within Rv0248c at 299.327 kb on - strand, within Rv0248c at 299.327 kb on - strand, within Rv0248c at 299.464 kb on - strand, within Rv0248c at 299.467 kb on + strand, within Rv0248c at 299.638 kb on + strand, within Rv0248c at 299.883 kb on - strand, within Rv0248c at 300.320 kb on - strand, within Rv0248c at 300.494 kb on - strand, within Rv0248c at 300.549 kb on - strand, within Rv0248c at 300.804 kb on - strand at 300.886 kb on + strand at 301.052 kb on - strand, within Rv0249c at 301.186 kb on + strand, within Rv0249c at 301.234 kb on + strand, within Rv0249c at 301.291 kb on + strand, within Rv0249c at 301.347 kb on + strand, within Rv0249c at 301.444 kb on + strand, within Rv0249c at 301.460 kb on - strand, within Rv0249c at 301.513 kb on + strand, within Rv0249c at 301.513 kb on + strand, within Rv0249c at 301.658 kb on - strand at 301.679 kb on + strand at 301.680 kb on - strand at 301.694 kb on + strand at 301.694 kb on + strand at 301.794 kb on - strand, within Rv0250c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 298,105 - -1.0 298,146 + +0.3 298,253 + Rv0247c 0.18 +0.7 299,230 - Rv0248c 0.19 +3.0 299,240 - Rv0248c 0.19 +4.0 299,327 - Rv0248c 0.24 +0.7 299,327 - Rv0248c 0.24 +1.9 299,464 - Rv0248c 0.31 +4.1 299,467 + Rv0248c 0.31 +2.1 299,638 + Rv0248c 0.40 +2.1 299,883 - Rv0248c 0.53 +1.5 300,320 - Rv0248c 0.75 +0.7 300,494 - Rv0248c 0.84 +1.8 300,549 - Rv0248c 0.87 +2.4 300,804 - +4.6 300,886 + +1.1 301,052 - Rv0249c 0.27 +2.1 301,186 + Rv0249c 0.43 +2.0 301,234 + Rv0249c 0.49 +2.0 301,291 + Rv0249c 0.56 +1.7 301,347 + Rv0249c 0.62 +3.3 301,444 + Rv0249c 0.74 -0.3 301,460 - Rv0249c 0.76 +1.6 301,513 + Rv0249c 0.83 +1.9 301,513 + Rv0249c 0.83 +0.7 301,658 - +2.4 301,679 + +1.7 301,680 - -1.0 301,694 + +0.9 301,694 + +1.3 301,794 - Rv0250c 0.20 -2.3
Or see this region's nucleotide sequence