Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0035 and Rv0036c are separated by 108 nucleotides Rv0036c and Rv0037c are separated by 47 nucleotides Rv0037c and Rv0038 are separated by 101 nucleotides Rv0038 and Rv0039c are separated by 91 nucleotides
Rv0035: Rv0035 - Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 37,259 to 38,947
Rv0035
Rv0036c: Rv0036c - Conserved protein, at 39,056 to 39,829
Rv0036c
Rv0037c: Rv0037c - Probable conserved integral membrane protein, at 39,877 to 41,202
Rv0037c
Rv0038: Rv0038 - Conserved protein, at 41,304 to 41,912
Rv0038
Rv0039c: Rv0039c - Possible conserved transmembrane protein, at 42,004 to 42,351
Rv0039c
Position (kb) 39
40
41
42 Strain fitness (log2 ratio) -2
-1
0
1
2 at 39.290 kb on + strand, within Rv0036c at 39.291 kb on - strand, within Rv0036c at 39.291 kb on - strand, within Rv0036c at 39.291 kb on - strand, within Rv0036c at 39.343 kb on + strand, within Rv0036c at 39.344 kb on - strand, within Rv0036c at 39.845 kb on + strand at 39.874 kb on - strand at 39.878 kb on + strand at 39.937 kb on + strand at 39.938 kb on - strand at 39.941 kb on + strand at 39.967 kb on + strand at 40.025 kb on + strand, within Rv0037c at 40.025 kb on + strand, within Rv0037c at 40.025 kb on + strand, within Rv0037c at 40.025 kb on + strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.026 kb on - strand, within Rv0037c at 40.142 kb on - strand, within Rv0037c at 40.156 kb on + strand, within Rv0037c at 40.156 kb on + strand, within Rv0037c at 40.156 kb on + strand, within Rv0037c at 40.157 kb on - strand, within Rv0037c at 40.157 kb on - strand, within Rv0037c at 40.238 kb on + strand, within Rv0037c at 40.238 kb on + strand, within Rv0037c at 40.239 kb on - strand, within Rv0037c at 40.474 kb on + strand, within Rv0037c at 40.474 kb on + strand, within Rv0037c at 40.475 kb on - strand, within Rv0037c at 40.475 kb on - strand, within Rv0037c at 40.496 kb on + strand, within Rv0037c at 40.543 kb on + strand, within Rv0037c at 40.544 kb on - strand, within Rv0037c at 40.849 kb on + strand, within Rv0037c at 41.180 kb on - strand at 41.248 kb on + strand at 41.374 kb on + strand, within Rv0038 at 41.374 kb on + strand, within Rv0038 at 41.374 kb on + strand, within Rv0038 at 41.375 kb on - strand, within Rv0038 at 41.427 kb on + strand, within Rv0038 at 41.496 kb on + strand, within Rv0038 at 41.497 kb on - strand, within Rv0038 at 41.497 kb on - strand, within Rv0038 at 41.633 kb on - strand, within Rv0038 at 41.911 kb on - strand at 41.916 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 39,290 + Rv0036c 0.30 -1.7 39,291 - Rv0036c 0.30 -0.7 39,291 - Rv0036c 0.30 +0.3 39,291 - Rv0036c 0.30 -0.7 39,343 + Rv0036c 0.37 -1.2 39,344 - Rv0036c 0.37 -0.5 39,845 + -0.3 39,874 - -0.7 39,878 + -2.1 39,937 + +1.6 39,938 - -0.9 39,941 + +0.0 39,967 + +1.1 40,025 + Rv0037c 0.11 -2.2 40,025 + Rv0037c 0.11 +0.3 40,025 + Rv0037c 0.11 +2.3 40,025 + Rv0037c 0.11 +0.7 40,026 - Rv0037c 0.11 -1.6 40,026 - Rv0037c 0.11 -1.0 40,026 - Rv0037c 0.11 -1.5 40,026 - Rv0037c 0.11 -1.0 40,026 - Rv0037c 0.11 -1.1 40,026 - Rv0037c 0.11 -0.0 40,026 - Rv0037c 0.11 -0.6 40,026 - Rv0037c 0.11 -0.4 40,026 - Rv0037c 0.11 +0.6 40,026 - Rv0037c 0.11 -1.3 40,142 - Rv0037c 0.20 -0.4 40,156 + Rv0037c 0.21 -1.4 40,156 + Rv0037c 0.21 -1.5 40,156 + Rv0037c 0.21 -0.9 40,157 - Rv0037c 0.21 -1.0 40,157 - Rv0037c 0.21 -1.1 40,238 + Rv0037c 0.27 -0.8 40,238 + Rv0037c 0.27 +1.0 40,239 - Rv0037c 0.27 -0.8 40,474 + Rv0037c 0.45 -0.3 40,474 + Rv0037c 0.45 +0.6 40,475 - Rv0037c 0.45 -1.2 40,475 - Rv0037c 0.45 -0.5 40,496 + Rv0037c 0.47 -1.4 40,543 + Rv0037c 0.50 -0.8 40,544 - Rv0037c 0.50 -0.7 40,849 + Rv0037c 0.73 -0.7 41,180 - +0.6 41,248 + -0.9 41,374 + Rv0038 0.11 +1.5 41,374 + Rv0038 0.11 +1.3 41,374 + Rv0038 0.11 +0.3 41,375 - Rv0038 0.12 +2.0 41,427 + Rv0038 0.20 +1.3 41,496 + Rv0038 0.32 +1.2 41,497 - Rv0038 0.32 -0.4 41,497 - Rv0038 0.32 -0.7 41,633 - Rv0038 0.54 +1.0 41,911 - +1.3 41,916 - +1.7
Or see this region's nucleotide sequence