Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3509c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,936,708	+				+1.4
3,936,709	-				+0.3
3,936,709	-				+1.4
3,936,713	+				-1.0
3,936,760	+				+0.1
3,936,858	+				+3.4
3,936,858	+				-0.4
3,936,859	-				+1.4
3,936,859	-				+1.0
3,936,859	-				-1.0
3,936,859	-				+2.8
3,936,859	-				-0.2
3,936,879	-				+0.9
3,936,901	+				+0.0
3,936,902	-				-0.2
3,936,997	-				+1.0
3,937,036	+		Rv3509c	0.10	-0.1
3,937,037	-		Rv3509c	0.10	+2.8
3,937,130	+		Rv3509c	0.16	+0.4
3,937,130	+		Rv3509c	0.16	+0.5
3,937,130	+		Rv3509c	0.16	+0.6
3,937,130	+		Rv3509c	0.16	+0.6
3,937,131	-		Rv3509c	0.16	+0.3
3,937,131	-		Rv3509c	0.16	+1.8
3,937,131	-		Rv3509c	0.16	+0.1
3,937,185	+		Rv3509c	0.20	-1.4
3,937,190	+		Rv3509c	0.20	+0.6
3,937,190	+		Rv3509c	0.20	-0.1
3,937,191	-		Rv3509c	0.20	+0.8
3,937,299	+		Rv3509c	0.27	+1.2
3,937,300	-		Rv3509c	0.27	-1.2
3,937,356	+		Rv3509c	0.31	-1.0
3,937,356	+		Rv3509c	0.31	+0.5
3,937,357	-		Rv3509c	0.31	-0.2
3,937,357	-		Rv3509c	0.31	+1.4
3,937,357	-		Rv3509c	0.31	-0.2
3,937,588	-		Rv3509c	0.46	+0.1
3,937,748	-		Rv3509c	0.56	+2.8
3,938,117	+		Rv3509c	0.80	+0.4
3,938,118	-		Rv3509c	0.80	+0.6
3,938,252	+		Rv3509c	0.89	+0.3
3,938,253	-		Rv3509c	0.89	+0.8
3,938,323	+				+1.8
3,938,565	-		Rv3510c	0.17	-0.2
3,938,641	+		Rv3510c	0.26	+1.4
3,938,641	+		Rv3510c	0.26	-0.3
3,938,641	+		Rv3510c	0.26	+1.5
3,938,660	-		Rv3510c	0.29	+0.6
3,938,711	-		Rv3510c	0.35	-0.9
3,938,770	+		Rv3510c	0.42	+1.0
3,938,770	+		Rv3510c	0.42	-0.7
3,938,771	-		Rv3510c	0.42	-0.3
3,938,771	-		Rv3510c	0.42	+0.5
3,938,872	+		Rv3510c	0.54	+1.2
3,938,873	-		Rv3510c	0.54	+0.2
3,938,876	-		Rv3510c	0.54	+0.8
3,938,876	-		Rv3510c	0.54	-0.7
3,938,905	-		Rv3510c	0.58	-1.5
3,939,203	+				+0.0
3,939,291	+				+0.4
3,939,332	+				-0.2
3,939,332	+				+1.2
3,939,333	-				-0.2
3,939,333	-				+0.0
3,939,397	-				+0.5
3,939,397	-				+0.1