Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3485c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,903,676	-		Rv3484	0.39	-1.3
3,903,759	+		Rv3484	0.44	-0.2
3,903,759	+		Rv3484	0.44	-3.0
3,903,768	+		Rv3484	0.45	-1.0
3,903,769	-		Rv3484	0.45	+0.1
3,903,850	+		Rv3484	0.50	+0.0
3,903,850	+		Rv3484	0.50	-1.4
3,904,081	-		Rv3484	0.65	-1.7
3,904,142	-		Rv3484	0.69	-1.7
3,904,142	-		Rv3484	0.69	-0.6
3,904,460	+		Rv3484	0.90	-1.8
3,904,461	-		Rv3484	0.90	-1.7
3,904,527	+				-1.6
3,904,528	-				-0.1
3,904,528	-				-1.3
3,904,528	-				-2.0
3,904,528	-				-0.6
3,904,536	+				-2.1
3,904,614	+				+3.4
3,904,614	+				-0.4
3,904,615	-				-0.4
3,904,615	-				-0.2
3,904,618	+				-1.6
3,904,618	+				+1.8
3,904,618	+				-0.2
3,904,618	+				-0.4
3,904,618	+				-1.6
3,904,619	-				-0.8
3,904,619	-				-2.3
3,904,619	-				-0.4
3,904,619	-				+0.5
3,904,619	-				-2.0
3,904,619	-				+0.3
3,904,619	-				+0.4
3,904,619	-				+0.2
3,904,623	+				+0.3
3,904,772	+		Rv3485c	0.16	-2.8
3,904,773	-		Rv3485c	0.16	+0.2
3,904,808	+		Rv3485c	0.20	-0.7
3,904,877	-		Rv3485c	0.27	-1.8
3,904,981	-		Rv3485c	0.38	-0.4
3,905,085	+		Rv3485c	0.49	-0.0
3,905,085	+		Rv3485c	0.49	+0.5
3,905,085	+		Rv3485c	0.49	-0.3
3,905,085	+		Rv3485c	0.49	+0.1
3,905,086	-		Rv3485c	0.49	-1.4
3,905,086	-		Rv3485c	0.49	-1.4
3,905,272	-		Rv3485c	0.69	-0.2
3,905,272	-		Rv3485c	0.69	-1.0
3,905,272	-		Rv3485c	0.69	+0.2
3,905,272	-		Rv3485c	0.69	-0.3
3,905,425	-		Rv3485c	0.85	-1.1
3,905,626	+				-0.4
3,905,627	-				-0.8
3,905,686	-				+0.1
3,905,686	-				-0.4
3,905,771	-				-0.6
3,905,804	+				+0.4
3,905,804	+				+0.6
3,905,804	+				-0.4
3,905,804	+				-0.4
3,905,804	+				-0.7
3,905,804	+				-0.1
3,905,804	+				-0.3
3,905,804	+				-0.5
3,905,805	-				-0.9
3,905,805	-				-0.9
3,905,806	+				-0.5
3,905,807	-				-0.0
3,905,807	-				-1.9
3,905,860	-		Rv3486	0.20	-0.1
3,905,860	-		Rv3486	0.20	-1.0
3,906,076	+		Rv3486	0.68	-0.7
3,906,176	-				-0.6
3,906,176	-				+0.6
3,906,176	-				-1.7
3,906,176	-				-0.6
3,906,180	-				+0.3
3,906,232	+				-0.6
3,906,376	-		Rv3487c	0.24	-0.7
3,906,461	+		Rv3487c	0.34	+0.8
3,906,461	+		Rv3487c	0.34	-0.7
3,906,462	-		Rv3487c	0.35	-0.2
3,906,462	-		Rv3487c	0.35	-0.8
3,906,462	-		Rv3487c	0.35	-0.3
3,906,505	+		Rv3487c	0.40	+0.6
3,906,505	+		Rv3487c	0.40	-0.8
3,906,505	+		Rv3487c	0.40	-0.8
3,906,505	+		Rv3487c	0.40	+0.1
3,906,505	+		Rv3487c	0.40	+0.2
3,906,506	-		Rv3487c	0.40	+0.2
3,906,506	-		Rv3487c	0.40	-1.2