Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3360

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3359 and Rv3360 are separated by 116 nucleotidesRv3360 and Rv3361c overlap by 4 nucleotidesRv3361c and Rv3362c are separated by 6 nucleotides Rv3359: Rv3359 - Possible oxidoreductase, at 3,771,344 to 3,772,534 Rv3359 Rv3360: Rv3360 - Conserved hypothetical protein, at 3,772,651 to 3,773,019 Rv3360 Rv3361c: Rv3361c - Conserved protein, at 3,773,016 to 3,773,567 Rv3361c Rv3362c: Rv3362c - Probable ATP/GTP-binding protein, at 3,773,574 to 3,774,155 Rv3362c Position (kb) 3772 3773 3774Strain fitness (log2 ratio) -2 -1 0 1at 3771.862 kb on + strand, within Rv3359at 3771.863 kb on - strand, within Rv3359at 3771.863 kb on - strand, within Rv3359at 3771.863 kb on - strand, within Rv3359at 3771.866 kb on + strand, within Rv3359at 3771.866 kb on + strand, within Rv3359at 3771.866 kb on + strand, within Rv3359at 3771.866 kb on + strand, within Rv3359at 3771.866 kb on + strand, within Rv3359at 3771.866 kb on + strand, within Rv3359at 3771.867 kb on - strand, within Rv3359at 3771.867 kb on - strand, within Rv3359at 3771.948 kb on + strand, within Rv3359at 3772.145 kb on + strand, within Rv3359at 3772.145 kb on + strand, within Rv3359at 3772.146 kb on - strand, within Rv3359at 3772.146 kb on - strand, within Rv3359at 3772.146 kb on - strand, within Rv3359at 3772.248 kb on - strand, within Rv3359at 3772.248 kb on - strand, within Rv3359at 3772.474 kb on + strandat 3772.475 kb on - strandat 3772.475 kb on - strandat 3772.532 kb on + strandat 3772.532 kb on + strandat 3772.621 kb on + strandat 3772.905 kb on + strand, within Rv3360at 3772.905 kb on + strand, within Rv3360at 3772.906 kb on - strand, within Rv3360at 3772.906 kb on - strand, within Rv3360at 3773.017 kb on + strandat 3773.018 kb on - strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL
remove
3,771,862 + Rv3359 0.43 -0.1
3,771,863 - Rv3359 0.44 +1.1
3,771,863 - Rv3359 0.44 -0.5
3,771,863 - Rv3359 0.44 -1.3
3,771,866 + Rv3359 0.44 +0.4
3,771,866 + Rv3359 0.44 -0.6
3,771,866 + Rv3359 0.44 +0.5
3,771,866 + Rv3359 0.44 -1.0
3,771,866 + Rv3359 0.44 -0.3
3,771,866 + Rv3359 0.44 +0.8
3,771,867 - Rv3359 0.44 -0.9
3,771,867 - Rv3359 0.44 -1.3
3,771,948 + Rv3359 0.51 -0.5
3,772,145 + Rv3359 0.67 -0.7
3,772,145 + Rv3359 0.67 +0.1
3,772,146 - Rv3359 0.67 -0.8
3,772,146 - Rv3359 0.67 +0.0
3,772,146 - Rv3359 0.67 +0.3
3,772,248 - Rv3359 0.76 -0.9
3,772,248 - Rv3359 0.76 -0.4
3,772,474 + -1.9
3,772,475 - -0.5
3,772,475 - -0.4
3,772,532 + -1.3
3,772,532 + -0.3
3,772,621 + +1.3
3,772,905 + Rv3360 0.69 -0.5
3,772,905 + Rv3360 0.69 -2.2
3,772,906 - Rv3360 0.69 -1.3
3,772,906 - Rv3360 0.69 -0.7
3,773,017 + -0.1
3,773,018 - -0.0

Or see this region's nucleotide sequence