Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3343c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,728,699	+		Rv3342	0.10	+0.2
3,729,134	-		Rv3342	0.70	-0.6
3,729,212	+		Rv3342	0.80	-0.5
3,729,468	-				+1.8
3,729,938	-				+0.2
3,730,018	-				+0.4
3,730,058	-				+0.6
3,730,353	-		Rv3343c	0.13	-0.5
3,730,377	-		Rv3343c	0.13	-0.3
3,731,157	+		Rv3343c	0.24	-0.5
3,731,712	+		Rv3343c	0.31	+0.8
3,731,712	+		Rv3343c	0.31	-1.3
3,731,712	+		Rv3343c	0.31	-0.6
3,731,712	+		Rv3343c	0.31	+0.1
3,731,712	+		Rv3343c	0.31	-0.4
3,731,712	+		Rv3343c	0.31	-0.1
3,731,712	+		Rv3343c	0.31	+0.5
3,731,713	-		Rv3343c	0.31	+4.4
3,731,713	-		Rv3343c	0.31	+0.5
3,731,713	-		Rv3343c	0.31	-0.1
3,731,713	-		Rv3343c	0.31	-0.3
3,731,713	-		Rv3343c	0.31	-1.1
3,731,725	+		Rv3343c	0.31	-0.2
3,731,725	+		Rv3343c	0.31	-1.0
3,731,725	+		Rv3343c	0.31	-1.2
3,731,725	+		Rv3343c	0.31	+1.6
3,731,725	+		Rv3343c	0.31	-0.1
3,731,725	+		Rv3343c	0.31	-0.2
3,731,726	-		Rv3343c	0.31	-0.3
3,731,726	-		Rv3343c	0.31	-0.2
3,731,735	-		Rv3343c	0.31	+0.3
3,731,749	-		Rv3343c	0.31	+0.5
3,731,825	+		Rv3343c	0.33	+1.4
3,731,825	+		Rv3343c	0.33	-0.1
3,731,825	+		Rv3343c	0.33	-1.7
3,731,826	-		Rv3343c	0.33	+0.1
3,731,826	-		Rv3343c	0.33	+0.9
3,731,826	-		Rv3343c	0.33	-0.7
3,731,826	-		Rv3343c	0.33	+1.8
3,731,826	-		Rv3343c	0.33	-0.1
3,731,854	-		Rv3343c	0.33	+0.2
3,732,081	-		Rv3343c	0.36	+0.7
3,732,105	-		Rv3343c	0.36	-0.1
3,732,105	-		Rv3343c	0.36	+0.2
3,733,095	+		Rv3343c	0.49	+0.6
3,733,126	+		Rv3343c	0.50	+0.5
3,733,328	-		Rv3343c	0.52	-2.0
3,733,473	+		Rv3343c	0.54	+1.0
3,733,520	-		Rv3343c	0.55	+1.1
3,733,520	-		Rv3343c	0.55	-0.4
3,733,520	-		Rv3343c	0.55	+0.6
3,733,664	+		Rv3343c	0.57	+0.8
3,733,664	+		Rv3343c	0.57	+0.2
3,733,665	-		Rv3343c	0.57	+0.7
3,733,692	+		Rv3343c	0.57	+1.8
3,733,693	-		Rv3343c	0.57	+3.4
3,733,693	-		Rv3343c	0.57	+1.2
3,733,693	-		Rv3343c	0.57	+1.8
3,733,693	-		Rv3343c	0.57	-0.2
3,733,831	+		Rv3343c	0.59	-0.6
3,733,979	+		Rv3343c	0.61	+0.5
3,733,980	-		Rv3343c	0.61	+1.8
3,734,764	-		Rv3343c	0.71	+0.3
3,734,764	-		Rv3343c	0.71	+1.8
3,734,764	-		Rv3343c	0.71	+0.4
3,734,767	+		Rv3343c	0.71	+0.6
3,734,767	+		Rv3343c	0.71	+0.0
3,734,768	-		Rv3343c	0.71	-0.2
3,734,768	-		Rv3343c	0.71	+0.8
3,734,919	+		Rv3343c	0.73	+0.2
3,735,160	+		Rv3343c	0.77	-1.3
3,735,276	+		Rv3343c	0.78	+0.7
3,735,512	+		Rv3343c	0.81	-1.2
3,735,551	-		Rv3343c	0.82	+0.2
3,735,551	-		Rv3343c	0.82	+0.8
3,735,551	-		Rv3343c	0.82	+2.2
3,735,593	-		Rv3343c	0.82	-1.0
3,735,593	-		Rv3343c	0.82	-0.2
3,735,693	+		Rv3343c	0.84	-0.2
3,735,693	+		Rv3343c	0.84	+0.6
3,736,286	+				-1.1
3,736,287	-				+1.8
3,736,287	-				+1.8
3,736,287	-				-1.3
3,736,287	-				-0.8
3,736,287	-				-0.8
3,736,316	+				+1.2
3,736,317	-				+0.5
3,736,476	-				+0.3
3,736,517	+				+0.6
3,736,565	+				+0.4
3,736,585	+				-0.7
3,736,585	+				+0.1
3,736,586	-				+0.5
3,736,586	-				+1.2
3,736,770	+				+0.8
3,736,770	+				-0.6
3,736,771	-				+0.4
3,736,771	-				+0.9
3,736,887	+				-0.3
3,736,887	+				+0.8
3,736,888	-				+0.8
3,736,888	-				+0.8
3,736,889	+				+0.2
3,736,889	+				-3.3
3,736,889	+				+0.5
3,736,890	-				+1.5
3,736,890	-				+0.1
3,736,890	-				+0.3
3,736,891	+				+0.2
3,736,891	+				+1.5
3,736,891	+				-0.3
3,736,891	+				+1.2
3,736,891	+				+0.5
3,736,891	+				+2.8
3,736,892	-				+0.1
3,736,892	-				-1.3
3,736,892	-				-0.4
3,736,892	-				+0.7
3,736,892	-				-0.0
3,737,592	+		Rv3344c	0.42	+0.8
3,737,592	+		Rv3344c	0.42	+0.1
3,737,592	+		Rv3344c	0.42	-0.0
3,737,592	+		Rv3344c	0.42	+0.2
3,737,592	+		Rv3344c	0.42	+1.8
3,737,593	-		Rv3344c	0.42	+0.5