Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3164c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3163c and Rv3164c are separated by 29 nucleotidesRv3164c and Rv3165c are separated by 7 nucleotidesRv3165c and Rv3166c overlap by 4 nucleotides Rv3163c: Rv3163c - Possible conserved secreted protein, at 3,531,642 to 3,532,913 Rv3163c Rv3164c: Rv3164c - Probable methanol dehydrogenase transcriptional regulatory protein MoxR3, at 3,532,943 to 3,533,905 Rv3164c Rv3165c: Rv3165c - Unknown protein, at 3,533,913 to 3,534,395 Rv3165c Rv3166c: Rv3166c - Conserved hypothetical protein, at 3,534,392 to 3,535,351 Rv3166c Position (kb) 3532 3533 3534Strain fitness (log2 ratio) -2 -1 0 1at 3532.204 kb on + strand, within Rv3163cat 3532.205 kb on - strand, within Rv3163cat 3532.305 kb on + strand, within Rv3163cat 3532.305 kb on + strand, within Rv3163cat 3532.305 kb on + strand, within Rv3163cat 3532.306 kb on - strand, within Rv3163cat 3532.325 kb on - strand, within Rv3163cat 3533.427 kb on + strand, within Rv3164cat 3533.427 kb on + strand, within Rv3164cat 3533.428 kb on - strand, within Rv3164cat 3533.439 kb on + strand, within Rv3164cat 3533.900 kb on - strandat 3533.916 kb on + strandat 3534.080 kb on + strand, within Rv3165cat 3534.395 kb on + strandat 3534.526 kb on + strand, within Rv3166cat 3534.639 kb on + strand, within Rv3166cat 3534.639 kb on + strand, within Rv3166cat 3534.805 kb on + strand, within Rv3166c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL
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3,532,204 + Rv3163c 0.44 -0.2
3,532,205 - Rv3163c 0.44 +1.2
3,532,305 + Rv3163c 0.52 -0.5
3,532,305 + Rv3163c 0.52 +1.3
3,532,305 + Rv3163c 0.52 -0.6
3,532,306 - Rv3163c 0.52 +0.6
3,532,325 - Rv3163c 0.54 +0.1
3,533,427 + Rv3164c 0.50 -0.5
3,533,427 + Rv3164c 0.50 -2.5
3,533,428 - Rv3164c 0.50 -1.1
3,533,439 + Rv3164c 0.52 -1.4
3,533,900 - -1.4
3,533,916 + +0.9
3,534,080 + Rv3165c 0.35 -1.1
3,534,395 + -0.6
3,534,526 + Rv3166c 0.14 -0.7
3,534,639 + Rv3166c 0.26 -0.6
3,534,639 + Rv3166c 0.26 -1.0
3,534,805 + Rv3166c 0.43 -0.5

Or see this region's nucleotide sequence