Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3086

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,451,181	+		Rv3085	0.31	+0.3
3,451,203	-		Rv3085	0.34	+0.6
3,451,697	+				-1.2
3,451,697	+				+0.9
3,451,756	+				+0.2
3,451,756	+				-0.8
3,451,881	-				+1.3
3,451,881	-				+0.7
3,451,881	-				-0.7
3,451,881	-				-0.8
3,451,933	-		Rv3086	0.14	-0.8
3,452,066	+		Rv3086	0.26	-1.0
3,452,351	+		Rv3086	0.51	-0.8
3,452,351	+		Rv3086	0.51	-0.9
3,452,407	+		Rv3086	0.57	+1.0
3,452,408	-		Rv3086	0.57	+0.0
3,452,408	-		Rv3086	0.57	-1.1
3,452,408	-		Rv3086	0.57	+0.0
3,452,408	-		Rv3086	0.57	-0.0
3,452,411	+		Rv3086	0.57	+1.9
3,452,412	-		Rv3086	0.57	+0.4
3,452,412	-		Rv3086	0.57	+0.3
3,452,810	+				-2.0
3,452,810	+				-1.8
3,452,961	+				-2.6
3,452,962	-				+0.8
3,452,983	-				+0.0
3,453,105	+		Rv3087	0.13	+1.3
3,453,387	+		Rv3087	0.33	-0.8
3,453,388	-		Rv3087	0.33	+2.2
3,453,388	-		Rv3087	0.33	+1.8
3,453,388	-		Rv3087	0.33	-0.9
3,453,760	-		Rv3087	0.59	+1.3
3,453,760	-		Rv3087	0.59	-0.7
3,453,856	-		Rv3087	0.66	-0.3
3,453,870	+		Rv3087	0.67	+1.9