Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2974c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
3,329,246	-		Rv2973c	0.68	-1.0
3,329,417	+		Rv2973c	0.76	-0.1
3,329,491	-		Rv2973c	0.79	+1.9
3,329,579	+		Rv2973c	0.83	-0.4
3,329,580	-		Rv2973c	0.83	-0.5
3,329,738	+				-2.1
3,329,739	-				+0.9
3,329,829	-				-0.7
3,329,841	-				+1.3
3,329,935	+				-0.4
3,329,936	-				+0.8
3,330,082	-				-0.9
3,330,375	+		Rv2974c	0.30	+0.5
3,330,408	-		Rv2974c	0.32	+1.4
3,330,408	-		Rv2974c	0.32	-1.5
3,330,440	-		Rv2974c	0.35	-1.3
3,330,440	-		Rv2974c	0.35	+0.6
3,330,440	-		Rv2974c	0.35	+1.9
3,330,480	+		Rv2974c	0.38	+0.9
3,330,481	-		Rv2974c	0.38	+1.9
3,330,751	-		Rv2974c	0.57	-0.6
3,330,751	-		Rv2974c	0.57	-0.2
3,330,751	-		Rv2974c	0.57	-0.6
3,330,757	+		Rv2974c	0.57	-1.4
3,330,758	-		Rv2974c	0.57	-2.5
3,330,758	-		Rv2974c	0.57	-0.2
3,330,859	+		Rv2974c	0.64	+1.3
3,330,860	-		Rv2974c	0.64	-0.5
3,330,860	-		Rv2974c	0.64	-0.7
3,330,860	-		Rv2974c	0.64	+0.9
3,330,860	-		Rv2974c	0.64	-0.1
3,331,166	+		Rv2974c	0.86	-2.1
3,331,442	+		Rv2975c	0.33	-1.7
3,331,442	+		Rv2975c	0.33	+0.5
3,331,613	+				-0.9
3,331,613	+				-1.3
3,331,614	-				-0.9
3,331,614	-				-0.1
3,331,614	-				-0.4
3,331,668	+				-0.6
3,331,669	-				+0.3