Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2778c and Rv2779c are separated by 31 nucleotides Rv2779c and Rv2780 are separated by 65 nucleotides Rv2780 and Rv2781c are separated by 14 nucleotides
Rv2778c: Rv2778c - Conserved protein, at 3,085,713 to 3,086,183
Rv2778c
Rv2779c: Rv2779c - Possible transcriptional regulatory protein (probably Lrp/AsnC-family), at 3,086,215 to 3,086,754
Rv2779c
Rv2780: Rv2780 - Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43), at 3,086,820 to 3,087,935
Rv2780
Rv2781c: Rv2781c - Possible alanine rich oxidoreductase, at 3,087,950 to 3,088,984
Rv2781c
Position (kb)
3086
3087
3088 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 3085.891 kb on + strand, within Rv2778c at 3085.892 kb on - strand, within Rv2778c at 3085.913 kb on + strand, within Rv2778c at 3085.914 kb on - strand, within Rv2778c at 3085.914 kb on - strand, within Rv2778c at 3085.926 kb on + strand, within Rv2778c at 3085.927 kb on - strand, within Rv2778c at 3085.927 kb on - strand, within Rv2778c at 3085.927 kb on - strand, within Rv2778c at 3086.118 kb on + strand, within Rv2778c at 3086.118 kb on + strand, within Rv2778c at 3086.195 kb on - strand at 3086.217 kb on - strand at 3086.217 kb on - strand at 3086.266 kb on - strand at 3086.376 kb on - strand, within Rv2779c at 3086.376 kb on - strand, within Rv2779c at 3086.376 kb on - strand, within Rv2779c at 3086.511 kb on - strand, within Rv2779c at 3086.593 kb on + strand, within Rv2779c at 3086.750 kb on - strand at 3086.798 kb on + strand at 3086.897 kb on - strand at 3087.029 kb on - strand, within Rv2780 at 3087.168 kb on + strand, within Rv2780 at 3087.200 kb on - strand, within Rv2780 at 3087.258 kb on + strand, within Rv2780 at 3087.258 kb on + strand, within Rv2780 at 3087.620 kb on - strand, within Rv2780 at 3087.667 kb on - strand, within Rv2780 at 3087.751 kb on - strand, within Rv2780 at 3088.173 kb on + strand, within Rv2781c at 3088.174 kb on - strand, within Rv2781c at 3088.521 kb on + strand, within Rv2781c at 3088.675 kb on - strand, within Rv2781c at 3088.701 kb on + strand, within Rv2781c at 3088.702 kb on - strand, within Rv2781c at 3088.704 kb on + strand, within Rv2781c at 3088.705 kb on - strand, within Rv2781c at 3088.735 kb on - strand, within Rv2781c at 3088.857 kb on + strand, within Rv2781c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 3,085,891 + Rv2778c 0.38 -1.0 3,085,892 - Rv2778c 0.38 +0.5 3,085,913 + Rv2778c 0.42 +0.3 3,085,914 - Rv2778c 0.43 +0.0 3,085,914 - Rv2778c 0.43 +2.0 3,085,926 + Rv2778c 0.45 +1.8 3,085,927 - Rv2778c 0.45 -0.4 3,085,927 - Rv2778c 0.45 -0.2 3,085,927 - Rv2778c 0.45 +3.4 3,086,118 + Rv2778c 0.86 +2.8 3,086,118 + Rv2778c 0.86 -1.0 3,086,195 - -0.5 3,086,217 - -0.0 3,086,217 - -1.1 3,086,266 - -0.9 3,086,376 - Rv2779c 0.30 -1.2 3,086,376 - Rv2779c 0.30 -0.7 3,086,376 - Rv2779c 0.30 -0.3 3,086,511 - Rv2779c 0.55 +2.8 3,086,593 + Rv2779c 0.70 -0.8 3,086,750 - -1.8 3,086,798 + -0.4 3,086,897 - -2.1 3,087,029 - Rv2780 0.19 -2.3 3,087,168 + Rv2780 0.31 -0.9 3,087,200 - Rv2780 0.34 -0.2 3,087,258 + Rv2780 0.39 -0.4 3,087,258 + Rv2780 0.39 +0.4 3,087,620 - Rv2780 0.72 +1.7 3,087,667 - Rv2780 0.76 -0.4 3,087,751 - Rv2780 0.83 +0.7 3,088,173 + Rv2781c 0.22 -0.7 3,088,174 - Rv2781c 0.22 -0.4 3,088,521 + Rv2781c 0.55 -0.4 3,088,675 - Rv2781c 0.70 -0.6 3,088,701 + Rv2781c 0.73 -1.1 3,088,702 - Rv2781c 0.73 -0.9 3,088,704 + Rv2781c 0.73 -0.4 3,088,705 - Rv2781c 0.73 -0.5 3,088,735 - Rv2781c 0.76 -0.3 3,088,857 + Rv2781c 0.88 -0.1
Or see this region's nucleotide sequence