Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2497c and Rv2498c are separated by 258 nucleotides Rv2498c and Rv2499c overlap by 4 nucleotides Rv2499c and Rv2500c overlap by 4 nucleotides
Rv2497c: Rv2497c - Probable branched-chain keto acid dehydrogenase E1 component, alpha subunit BkdA, at 2,810,993 to 2,812,096
Rv2497c
Rv2498c: Rv2498c - Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase), at 2,812,355 to 2,813,176
Rv2498c
Rv2499c: Rv2499c - Possible oxidase regulatory-related protein, at 2,813,173 to 2,813,730
Rv2499c
Rv2500c: Rv2500c - Possible acyl-CoA dehydrogenase FadE19 (MMGC), at 2,813,727 to 2,814,911
Rv2500c
Position (kb)
2812
2813
2814 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2811.379 kb on - strand, within Rv2497c at 2811.511 kb on - strand, within Rv2497c at 2811.561 kb on - strand, within Rv2497c at 2811.561 kb on - strand, within Rv2497c at 2811.776 kb on + strand, within Rv2497c at 2811.827 kb on + strand, within Rv2497c at 2811.828 kb on - strand, within Rv2497c at 2811.879 kb on + strand, within Rv2497c at 2811.880 kb on - strand, within Rv2497c at 2811.954 kb on + strand, within Rv2497c at 2811.993 kb on + strand at 2812.161 kb on + strand at 2812.284 kb on - strand at 2812.634 kb on + strand, within Rv2498c at 2812.634 kb on + strand, within Rv2498c at 2812.921 kb on + strand, within Rv2498c at 2812.921 kb on + strand, within Rv2498c at 2812.924 kb on - strand, within Rv2498c at 2812.969 kb on + strand, within Rv2498c at 2812.969 kb on + strand, within Rv2498c at 2813.600 kb on + strand, within Rv2499c at 2813.840 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 2,811,379 - Rv2497c 0.35 -0.0 2,811,511 - Rv2497c 0.47 -0.5 2,811,561 - Rv2497c 0.51 -0.6 2,811,561 - Rv2497c 0.51 -0.6 2,811,776 + Rv2497c 0.71 +0.1 2,811,827 + Rv2497c 0.76 +1.7 2,811,828 - Rv2497c 0.76 -2.0 2,811,879 + Rv2497c 0.80 +3.0 2,811,880 - Rv2497c 0.80 +2.2 2,811,954 + Rv2497c 0.87 -0.3 2,811,993 + -0.1 2,812,161 + -0.1 2,812,284 - -0.7 2,812,634 + Rv2498c 0.34 -2.2 2,812,634 + Rv2498c 0.34 -1.0 2,812,921 + Rv2498c 0.69 -0.2 2,812,921 + Rv2498c 0.69 -0.4 2,812,924 - Rv2498c 0.69 -0.6 2,812,969 + Rv2498c 0.75 -1.4 2,812,969 + Rv2498c 0.75 -1.5 2,813,600 + Rv2499c 0.77 -1.9 2,813,840 + -1.0
Or see this region's nucleotide sequence