Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2435c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,729,657	-		Rv2434c	0.37	+1.3
2,729,821	-		Rv2434c	0.49	+1.7
2,730,465	+				+0.0
2,730,580	-				+0.3
2,730,673	-				+2.6
2,730,741	+				+1.0
2,730,887	-		Rv2435c	0.15	+1.7
2,730,927	+		Rv2435c	0.17	+1.1
2,731,518	+		Rv2435c	0.44	-0.8
2,731,823	-		Rv2435c	0.58	-0.1
2,732,235	+		Rv2435c	0.77	-0.8
2,732,236	-		Rv2435c	0.77	+0.2
2,732,251	-		Rv2435c	0.77	-1.7
2,732,343	+		Rv2435c	0.81	-1.3
2,732,571	+				+0.4
2,732,605	+				-0.7
2,732,683	+				-1.1
2,732,811	+				+3.3
2,732,931	+				-0.0
2,732,974	+				-0.6
2,732,974	+				+2.2
2,732,975	-				+0.2
2,732,975	-				+0.9
2,733,251	-				-1.7
2,733,251	-				-0.5