Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2212

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,477,123	-				+1.9
2,477,183	+				-1.3
2,477,183	+				-2.5
2,477,184	-				+0.1
2,477,184	-				-0.6
2,477,184	-				+0.2
2,477,193	+				-0.2
2,477,268	+				-0.1
2,477,356	+		Rv2212	0.15	+0.3
2,477,356	+		Rv2212	0.15	+1.8
2,477,376	+		Rv2212	0.16	+2.0
2,477,377	-		Rv2212	0.16	-0.1
2,477,377	-		Rv2212	0.16	-0.0
2,477,377	-		Rv2212	0.16	-0.6
2,477,682	+		Rv2212	0.43	+0.8
2,477,766	+		Rv2212	0.51	-0.2
2,478,072	+		Rv2212	0.78	-1.1
2,478,102	+		Rv2212	0.80	+0.4
2,478,102	+		Rv2212	0.80	+2.8
2,478,325	-				+1.4
2,478,360	+				-0.1
2,478,360	+				-0.4
2,478,361	-				+0.0
2,478,361	-				+0.8
2,478,361	-				-0.8
2,478,727	-		Rv2213	0.25	-0.6
2,478,727	-		Rv2213	0.25	+3.3
2,478,780	-		Rv2213	0.29	+0.1