Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2102

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,362,475	+		Rv2101	0.73	-1.1
2,362,476	-		Rv2101	0.74	-1.9
2,362,476	-		Rv2101	0.74	-0.2
2,362,547	+		Rv2101	0.76	-0.8
2,362,580	+		Rv2101	0.77	-0.6
2,362,581	-		Rv2101	0.77	+0.9
2,362,883	+		Rv2101	0.87	+1.8
2,363,279	+				+1.1
2,363,279	+				+0.2
2,363,289	+				-0.0
2,363,290	-				-0.5
2,363,290	-				-0.1
2,363,439	+				-0.0
2,363,440	-				-0.3
2,363,440	-				-0.3
2,363,701	+		Rv2102	0.43	-2.1
2,363,763	+		Rv2102	0.52	-1.7
2,363,763	+		Rv2102	0.52	-0.8
2,363,764	-		Rv2102	0.52	-0.2
2,363,937	+		Rv2102	0.76	-1.1
2,363,937	+		Rv2102	0.76	-0.8
2,364,066	+				+0.1
2,364,067	-				-0.3
2,364,147	+		Rv2103c	0.14	+1.8
2,364,147	+		Rv2103c	0.14	-0.9
2,364,148	-		Rv2103c	0.14	-0.2
2,364,228	+		Rv2103c	0.33	+0.2
2,364,228	+		Rv2103c	0.33	+1.4
2,364,228	+		Rv2103c	0.33	-1.2
2,364,228	+		Rv2103c	0.33	+3.0
2,364,229	-		Rv2103c	0.33	+0.2
2,364,490	-				-1.7
2,364,528	+				+0.7
2,364,529	-				+1.0
2,364,845	-				-0.4