Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2066

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,322,566	-				-0.4
2,322,566	-				+0.5
2,322,566	-				+0.7
2,322,949	+		Rv2065	0.63	-1.2
2,322,950	-		Rv2065	0.63	+1.0
2,323,098	+		Rv2065	0.87	+4.9
2,323,099	-		Rv2065	0.87	+0.9
2,323,099	-		Rv2065	0.87	+1.7
2,323,281	-				-0.7
2,323,331	+		Rv2066	0.10	-0.4
2,323,331	+		Rv2066	0.10	-0.1
2,323,431	-		Rv2066	0.17	-0.1
2,323,431	-		Rv2066	0.17	-0.9
2,323,514	+		Rv2066	0.22	-0.4
2,323,515	-		Rv2066	0.22	-0.4
2,323,515	-		Rv2066	0.22	+0.2
2,323,515	-		Rv2066	0.22	-0.4
2,323,523	+		Rv2066	0.23	+0.3
2,323,523	+		Rv2066	0.23	-0.6
2,323,523	+		Rv2066	0.23	+0.6
2,323,524	-		Rv2066	0.23	+0.7
2,323,524	-		Rv2066	0.23	-0.1
2,323,524	-		Rv2066	0.23	-0.7
2,323,862	+		Rv2066	0.45	-1.6
2,323,863	-		Rv2066	0.45	-0.3
2,323,863	-		Rv2066	0.45	+1.7
2,323,863	-		Rv2066	0.45	-0.9
2,324,161	-		Rv2066	0.65	-1.1
2,324,161	-		Rv2066	0.65	+0.6
2,324,288	+		Rv2066	0.73	-2.9
2,324,384	+		Rv2066	0.79	-2.6
2,324,384	+		Rv2066	0.79	+0.0
2,324,384	+		Rv2066	0.79	+0.2
2,324,385	-		Rv2066	0.79	-2.5
2,324,385	-		Rv2066	0.79	-1.2
2,324,385	-		Rv2066	0.79	+0.2
2,324,385	-		Rv2066	0.79	+0.4
2,324,385	-		Rv2066	0.79	-0.7
2,324,385	-		Rv2066	0.79	-1.1
2,324,575	-				-1.7
2,324,669	-				-0.9
2,324,669	-				+0.7
2,324,669	-				-0.4
2,324,869	-		Rv2067c	0.18	+0.1
2,324,869	-		Rv2067c	0.18	-0.2
2,324,909	-		Rv2067c	0.21	-1.1
2,324,912	+		Rv2067c	0.22	-1.0
2,324,912	+		Rv2067c	0.22	-0.2
2,324,913	-		Rv2067c	0.22	+0.7
2,324,949	-		Rv2067c	0.25	+0.2
2,324,949	-		Rv2067c	0.25	+0.3
2,325,066	-		Rv2067c	0.34	-0.5
2,325,101	+		Rv2067c	0.37	-1.1
2,325,102	-		Rv2067c	0.37	+0.4
2,325,281	-		Rv2067c	0.52	-0.6
2,325,384	-		Rv2067c	0.60	-1.9
2,325,384	-		Rv2067c	0.60	-1.0
2,325,616	-		Rv2067c	0.79	-0.7