Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2024c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,267,871	+		Rv2023c	0.34	-0.2
2,268,032	+		Rv2023c	0.79	-1.2
2,268,032	+		Rv2023c	0.79	+1.6
2,268,032	+		Rv2023c	0.79	-0.3
2,268,154	+				-0.6
2,268,158	+				-0.4
2,268,253	+				-0.7
2,268,254	-				+1.2
2,268,264	+				+0.2
2,268,364	-		Rv2023A	0.21	+0.6
2,268,487	+		Rv2023A	0.48	-0.5
2,268,549	-		Rv2023A	0.61	+0.3
2,268,556	+		Rv2023A	0.63	-1.1
2,268,594	+		Rv2023A	0.71	+1.8
2,268,630	-		Rv2023A	0.79	-3.1
2,268,695	-				-0.7
2,268,695	-				-0.4
2,269,012	+		Rv2024c	0.21	-0.5
2,269,013	-		Rv2024c	0.21	-0.5
2,269,169	+		Rv2024c	0.31	-0.3
2,269,169	+		Rv2024c	0.31	+0.8
2,269,169	+		Rv2024c	0.31	+0.1
2,269,170	-		Rv2024c	0.31	-0.5
2,269,170	-		Rv2024c	0.31	-0.6
2,269,171	+		Rv2024c	0.31	-1.8
2,269,172	-		Rv2024c	0.31	-1.0
2,269,195	+		Rv2024c	0.32	-0.8
2,269,195	+		Rv2024c	0.32	-2.2
2,269,196	-		Rv2024c	0.32	+0.4
2,269,196	-		Rv2024c	0.32	-0.6
2,269,343	-		Rv2024c	0.42	-1.4
2,269,343	-		Rv2024c	0.42	-0.8
2,269,405	-		Rv2024c	0.46	-1.1
2,269,451	-		Rv2024c	0.49	+1.8
2,269,996	+		Rv2024c	0.84	-0.2
2,270,020	+		Rv2024c	0.86	+0.6
2,270,020	+		Rv2024c	0.86	+0.1
2,270,021	-		Rv2024c	0.86	-0.2
2,270,021	-		Rv2024c	0.86	-0.4
2,270,116	+				-0.5
2,270,149	+				-1.1
2,270,150	-				-1.4
2,270,240	+				-0.8
2,270,241	-				-0.0
2,270,374	+				+0.3
2,270,375	-				-1.4
2,270,408	-				-1.2
2,270,434	-				+0.1
2,270,434	-				-0.8
2,270,483	+				-1.2
2,270,483	+				+1.0
2,270,483	+				-0.6
2,270,483	+				-0.2
2,270,484	-				-0.8
2,270,638	+				-0.5
2,270,639	-				-0.3
2,270,639	-				-2.6
2,270,665	+				-0.9
2,270,740	+				-0.7
2,270,803	-				-0.4