Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2022c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,266,260	+		Rv2019	0.65	-0.8
2,266,310	+		Rv2019	0.77	-0.3
2,266,311	-		Rv2019	0.77	-0.2
2,266,311	-		Rv2019	0.77	+0.1
2,266,311	-		Rv2019	0.77	-2.1
2,266,311	-		Rv2019	0.77	+2.2
2,266,312	+		Rv2019	0.77	-0.4
2,266,313	-		Rv2019	0.78	-0.5
2,266,313	-		Rv2019	0.78	-0.3
2,266,367	+				-0.3
2,266,367	+				-0.8
2,266,367	+				+0.8
2,266,368	-				-1.6
2,266,403	+				-0.8
2,266,403	+				-0.2
2,266,404	-				-0.8
2,266,404	-				-1.6
2,266,404	-				-0.6
2,266,500	+		Rv2020c	0.26	-0.7
2,266,501	-		Rv2020c	0.27	-0.5
2,266,501	-		Rv2020c	0.27	-1.3
2,266,501	-		Rv2020c	0.27	+0.4
2,266,622	+		Rv2020c	0.67	-1.0
2,266,667	+		Rv2020c	0.82	-0.0
2,266,668	-		Rv2020c	0.82	-0.1
2,267,078	+		Rv2021c	0.89	+0.2
2,267,079	-		Rv2021c	0.90	+0.2
2,267,079	-		Rv2021c	0.90	+0.3
2,267,096	+				+3.3
2,267,096	+				+0.7
2,267,096	+				+1.8
2,267,097	-				-1.0
2,267,097	-				-0.5
2,267,120	+				-0.1
2,267,121	-				-2.5
2,267,121	-				-0.6
2,267,121	-				+1.2
2,267,216	+		Rv2022c	0.16	+0.5
2,267,244	+		Rv2022c	0.21	+0.8
2,267,418	+		Rv2022c	0.49	+0.2
2,267,438	+		Rv2022c	0.53	+0.0
2,267,439	-		Rv2022c	0.53	-2.0
2,267,515	+		Rv2022c	0.65	-0.4
2,267,515	+		Rv2022c	0.65	+0.8
2,267,516	-		Rv2022c	0.66	-1.1
2,267,546	+		Rv2022c	0.70	-0.9
2,267,558	+		Rv2022c	0.72	-0.8
2,267,580	+		Rv2022c	0.76	-0.1
2,267,641	+		Rv2022c	0.86	-0.8
2,267,641	+		Rv2022c	0.86	+0.2
2,267,641	+		Rv2022c	0.86	+0.3
2,267,642	-		Rv2022c	0.86	-1.4
2,267,674	+				+0.8
2,267,674	+				+0.4
2,267,675	-				-1.0
2,267,684	+				-0.7
2,267,684	+				+1.2
2,267,684	+				+0.1
2,267,871	+		Rv2023c	0.34	-0.2
2,268,032	+		Rv2023c	0.79	-1.2
2,268,032	+		Rv2023c	0.79	+1.6
2,268,032	+		Rv2023c	0.79	-0.3
2,268,154	+				-0.6
2,268,158	+				-0.4
2,268,253	+				-0.7
2,268,254	-				+1.2
2,268,264	+				+0.2
2,268,364	-		Rv2023A	0.21	+0.6
2,268,487	+		Rv2023A	0.48	-0.5
2,268,549	-		Rv2023A	0.61	+0.3
2,268,556	+		Rv2023A	0.63	-1.1
2,268,594	+		Rv2023A	0.71	+1.8
2,268,630	-		Rv2023A	0.79	-3.1
2,268,695	-				-0.7
2,268,695	-				-0.4