Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1854c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
2,101,013	-				-0.9
2,101,526	-		Rv1853	0.80	+0.4
2,101,619	-				-1.4
2,101,652	+				-0.5
2,101,665	+				-0.9
2,103,186	-				-1.3
2,103,242	+				+0.7
2,103,243	-				-1.3
2,103,269	-				-0.9
2,103,626	+		Rv1855c	0.48	+0.5
2,103,626	+		Rv1855c	0.48	-2.4
2,103,626	+		Rv1855c	0.48	+0.2
2,103,627	-		Rv1855c	0.48	-0.8
2,103,627	-		Rv1855c	0.48	-1.4
2,103,682	+		Rv1855c	0.54	+0.5
2,103,848	+		Rv1855c	0.72	-0.4
2,103,852	+		Rv1855c	0.72	+1.5
2,103,853	-		Rv1855c	0.72	+1.0
2,103,853	-		Rv1855c	0.72	+0.6
2,103,853	-		Rv1855c	0.72	-1.0
2,103,853	-		Rv1855c	0.72	+0.2
2,103,920	+		Rv1855c	0.80	+1.2
2,103,969	-		Rv1855c	0.85	+2.2
2,103,998	+		Rv1855c	0.88	+0.2