Experiment: 7H9 with Isoniazid 0.025 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1612 and Rv1613 overlap by 1 nucleotides Rv1613 and Rv1614 overlap by 1 nucleotides Rv1614 and Rv1615 are separated by 675 nucleotides
Rv1612: Rv1612 - Tryptophan synthase, beta subunit TrpB, at 1,811,127 to 1,812,359
Rv1612
Rv1613: Rv1613 - Probable tryptophan synthase, alpha subunit TrpA, at 1,812,359 to 1,813,171
Rv1613
Rv1614: Rv1614 - Possible prolipoprotein diacylglyceryl transferases Lgt, at 1,813,171 to 1,814,577
Rv1614
Rv1615: Rv1615 - Probable membrane protein, at 1,815,253 to 1,815,693
Rv1615
Position (kb)
1813
1814
1815 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1814.038 kb on + strand, within Rv1614 at 1814.038 kb on + strand, within Rv1614 at 1814.620 kb on + strand at 1814.621 kb on - strand at 1814.621 kb on - strand at 1814.707 kb on + strand at 1814.747 kb on - strand at 1814.756 kb on - strand at 1814.761 kb on - strand at 1814.850 kb on + strand at 1814.850 kb on + strand at 1814.850 kb on + strand at 1814.850 kb on + strand at 1814.851 kb on - strand at 1814.851 kb on - strand at 1814.861 kb on - strand at 1814.925 kb on - strand at 1815.409 kb on + strand, within Rv1615 at 1815.409 kb on + strand, within Rv1615 at 1815.409 kb on + strand, within Rv1615 at 1815.409 kb on + strand, within Rv1615 at 1815.539 kb on - strand, within Rv1615 at 1815.549 kb on + strand, within Rv1615
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Isoniazid 0.025 ug/mL remove 1,814,038 + Rv1614 0.62 +0.1 1,814,038 + Rv1614 0.62 +1.0 1,814,620 + -1.3 1,814,621 - -1.8 1,814,621 - -0.6 1,814,707 + -0.6 1,814,747 - -0.9 1,814,756 - -0.1 1,814,761 - -0.1 1,814,850 + -0.5 1,814,850 + -0.4 1,814,850 + +1.8 1,814,850 + -0.9 1,814,851 - -0.7 1,814,851 - -0.5 1,814,861 - -0.2 1,814,925 - -0.3 1,815,409 + Rv1615 0.35 -1.6 1,815,409 + Rv1615 0.35 +0.5 1,815,409 + Rv1615 0.35 +2.3 1,815,409 + Rv1615 0.35 -0.3 1,815,539 - Rv1615 0.65 -1.1 1,815,549 + Rv1615 0.67 -0.3
Or see this region's nucleotide sequence