Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1106c

Experiment: 7H9 with Isoniazid 0.025 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Isoniazid 0.025 ug/mL
1,231,978	+				-0.3
1,231,979	-				-0.5
1,232,415	+		Rv1105	0.20	-0.7
1,232,488	+		Rv1105	0.34	-0.3
1,232,488	+		Rv1105	0.34	-0.2
1,232,488	+		Rv1105	0.34	+1.8
1,232,489	-		Rv1105	0.34	-0.5
1,232,566	+		Rv1105	0.49	+1.0
1,232,726	-		Rv1105	0.80	-0.8
1,232,836	-				-1.6
1,232,914	+				-0.4
1,232,914	+				-0.7
1,232,914	+				-0.6
1,232,914	+				+0.7
1,232,915	-				+0.5
1,232,915	-				+0.6
1,232,915	-				-0.5
1,232,915	-				-0.5
1,232,917	+				-0.9
1,232,918	-				-0.5
1,232,965	+		Rv1106c	0.11	-0.0
1,232,965	+		Rv1106c	0.11	-2.3
1,232,966	-		Rv1106c	0.11	-0.9
1,233,013	+		Rv1106c	0.15	-1.0
1,233,013	+		Rv1106c	0.15	-0.6
1,233,094	-		Rv1106c	0.22	+1.8
1,233,179	+		Rv1106c	0.30	-0.7
1,233,180	-		Rv1106c	0.30	+0.7
1,233,286	+		Rv1106c	0.40	-0.4
1,233,286	+		Rv1106c	0.40	-0.7
1,233,286	+		Rv1106c	0.40	-1.7
1,233,287	-		Rv1106c	0.40	+1.0
1,233,287	-		Rv1106c	0.40	-0.3
1,233,287	-		Rv1106c	0.40	-0.3
1,233,287	-		Rv1106c	0.40	-0.8
1,233,484	+		Rv1106c	0.58	-0.2
1,233,506	+		Rv1106c	0.59	-0.6
1,233,507	-		Rv1106c	0.60	-1.9
1,233,650	+		Rv1106c	0.72	-1.4
1,233,651	-		Rv1106c	0.73	-1.4
1,234,027	-		Rv1107c	0.24	-0.8
1,234,154	-		Rv1107c	0.73	-0.1
1,234,366	+		Rv1108c	0.12	-0.9
1,234,366	+		Rv1108c	0.12	-0.3
1,234,367	-		Rv1108c	0.12	+0.6